{"id":6555,"date":"2020-10-20T15:44:00","date_gmt":"2020-10-20T20:44:00","guid":{"rendered":"https:\/\/shockwavemedical.com\/clinical-evidence\/disrupt-pad-iii-randomized-clinical-trial\/"},"modified":"2026-04-08T08:39:18","modified_gmt":"2026-04-08T13:39:18","slug":"pad-iii-rct","status":"publish","type":"clinical-evidence","link":"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/pad-iii-rct\/","title":{"rendered":"DISRUPT PAD III Randomized Clinical Trial"},"content":{"rendered":"\n\n\n<section id=\"block_a08def033e614cf42089c4b4c8edf741\" class=\"block block--primary-header u-darkMode u-bgColor_primary shockwave\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Background-Pulses.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">DISRUPT PAD III Randomized Clinical Trial <\/h1>\n\t\t\t<h3 class=\"sub-heading\">Shockwave Intravascular Lithotripsy (IVL) provides superior vessel prep and excellent long-term results in calcified vessels while preserving future treatment options.<\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/DISRUPT-PAD-III-Clinical-Hero-Image-14.png\" alt=\"DISRUPT PAD III RCT logo\" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t\t\t<div class=\"mobile-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Clinical-Hero-Images-mobile-13.png\" alt=\"DISRUPT PAD III Randomized Clinical Trial logo\" role=\"img\" aria-label=\"Foreground image for mobile\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 814px; --smush-placeholder-aspect-ratio: 814\/446;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n\n<section id=\"findings\" class=\"block block--content-3-or-4-up text_colors \" aria-labelledby=\"section-heading-findings\">\n\t<div class=\"container\">\n\n\t\t<!-- Header -->\n\t\t\t\t\t<header class=\"heading-row\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"section-heading-findings\" class=\"optional-heading\">\n\t\t\t\t\t\tKey Findings\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/header>\n\t\t\n\t\t<!-- Cards Section -->\n\t\t<ul class=\"cards three-cards\" role=\"list\">\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Superior Prep<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Shockwave IVL\u2019s unique mechanism of action (MOA) delivers significantly more luminal gain with lower dilation pressure and significantly lower dissections. <\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Preserved Options<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Shockwave IVL maintains control of the procedure by minimizing complications such as dissections, embolization and perforations. Shockwave IVL significantly reduces the need for bailout stents, preserving future treatment options.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Excellent Long-term Results<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Shockwave IVL has demonstrated excellent patency out to two years in a severely calcified patient population.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_8b074b8b9d100be3f729fceded0d44b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"design\" class=\"block block--study-design-patient-chars shockwave\" role=\"region\" aria-labelledby=\"design-heading\">\n\t<div class=\"container\">\n\t\t\t\t\t<div class=\"heading-row wysiwyg_styles\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"design-heading\" class=\"heading\">\n\t\t\t\t\t\tStudy Design & Characteristics\t\t\t\t\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"columns wysiwyg_styles\" aria-label=\"Study Design Columns\">\n\t\t\t<div class=\"columns-2-and-3\">\n\t\t\t\t<div class=\"column-2\">\n\t\t\t\t\t<p><strong>Objective: <\/strong><\/p>\n<p>To assess safety and effectiveness of IVL versus percutaneous transluminal angioplasty (PTA) as a vessel preparation strategy prior to definitive treatment with drug-coated balloon (DCB) +\/- stent in patients with calcified femoropopliteal lesions<\/p>\n<p><strong>Design: <\/strong><\/p>\n<ul>\n<li>Prospective<\/li>\n<li>Multicenter<\/li>\n<li>Single-blind<\/li>\n<li>Randomized clinical trial (RCT)<\/li>\n<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-3\">\n\t\t\t\t\t<p><strong>Primary Endpoint: <\/strong><\/p>\n<ul>\n<li>Procedural success (residual stenosis \u2264 30% without flow-limiting dissection)<\/li>\n<\/ul>\n<p><strong>Powered Secondary: <\/strong><\/p>\n<ul>\n<li>Primary patency at one year (freedom from clinically driven target lesion revascularization (CD-TLR) + freedom from restenosis determined by duplex ultrasound (US) + freedom from provisional stenting)<\/li>\n<\/ul>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"column-1\">\n\t\t\t\t<div class=\"column-1-content\">\n\t\t\t\t\t<div class=\"column-1-content-top\">\n\t\t\t\t\t\t306 superficial femoral artery (SFA)\/popliteal lesions\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"column-1-content-bottom\">\n\t\t\t\t\t\t83% severe calcification*; 129 mm* average calcified length\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-1-arrow\" aria-hidden=\"true\" aria-label=\"Arrow pointing downwards to indicate result\"><i class=\"fa-regular fa-arrow-down\"><\/i><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n\n<section id=\"block_1f7b59ff2d7977c42a9c8e061806e864\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">*IVL Arm<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"results\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_15c7f9b774524689206ef8a4aae4d1e7\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Superior Prep<\/h2>\n<p>Shockwave IVL\u2019s unique MOA delivers significantly more luminal gain with lower dilatation pressure and less need for post-dilatation.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-11077 lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2020\/10\/Superior-Prep-Table-Updated-01-300x128.png\" alt=\"Bar and icon graph illustrating superior procedural success and atraumatic treatment outcomes between Intravascular Lithotripsy (IVL) and Percutaneous Transluminal Angioplasty (PTA).\" width=\"1400\" height=\"596\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2020\/10\/Superior-Prep-Table-Updated-01-300x128.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2020\/10\/Superior-Prep-Table-Updated-01-1024x436.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2020\/10\/Superior-Prep-Table-Updated-01-768x327.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2020\/10\/Superior-Prep-Table-Updated-01-1536x654.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2020\/10\/Superior-Prep-Table-Updated-01.png 2000w\" data-sizes=\"(max-width: 1400px) 100vw, 1400px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1400px; --smush-placeholder-aspect-ratio: 1400\/596;\" \/><\/p>\n<h2>Preserved Options<\/h2>\n<p>Shockwave IVL maintains control of the procedure by minimizing complications such as dissections, embolization and perforations. Shockwave IVL significantly reduces the need for bailout stents, preserving future treatment options.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-6536 lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_2-300x124.png\" alt=\"Three-part infographic showing the clinical benefits of Intravascular Lithotripsy (IVL) compared to Percutaneous Transluminal Angioplasty (PTA) in terms of reduced dissections, lower complications, and reduced bailout stenting.\" width=\"1400\" height=\"577\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_2-300x124.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_2-1024x422.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_2-768x316.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_2-1536x633.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_2.png 2000w\" data-sizes=\"(max-width: 1400px) 100vw, 1400px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1400px; --smush-placeholder-aspect-ratio: 1400\/577;\" \/><\/p>\n<ul>\n<li><span class=\"legal_copy\">Embolic protection: Utilized in 1.3% of cases in Shockwave IVL treatment arm <\/span><\/li>\n<li><span class=\"legal_copy\">Provisional stent: Utilized if residual stenosis \u226550% by visual estimate or unresolved \u2265 type D dissection, and trans-lesional gradient > 10 mmHg<\/span><\/li>\n<\/ul>\n<h2>Excellent Long-term Results<\/h2>\n<p>Shockwave IVL has demonstrated excellent patency out to two years in a severely calcified patient population.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-6541 lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_3-300x152.png\" alt=\"Graph comparing primary patency rates over 24 months between two treatment groups: IVL + DCB (Intravascular Lithotripsy + Drug-Coated Balloon, in blue) and PTA + DCB (Percutaneous Transluminal Angioplasty + Drug-Coated Balloon, in gray).\" width=\"1400\" height=\"709\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_3-300x152.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_3-1024x519.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_3-768x389.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_3-1536x778.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_III_RCT_Global_White_3.png 2000w\" data-sizes=\"(max-width: 1400px) 100vw, 1400px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1400px; --smush-placeholder-aspect-ratio: 1400\/709;\" \/><\/p>\n<p>\u00a0<\/p>\n<p><strong>Number of subjects at risk:<\/strong><\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 48px;\">\n<tbody>\n<tr>\n<th style=\"width: 16.6667%; background-color: #eeeeee; border: max(0.0694444vw, 1px) solid #b6bfbf;\"><span class=\"TextRun SCXW208998347 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW208998347 BCX0\">Months After Index Procedure<\/span><\/span><\/th>\n<td style=\"width: 16.6667%; background-color: #ffffff;\"><strong><span class=\"TextRun SCXW53042425 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW53042425 BCX0\">0<\/span><\/span><\/strong><\/td>\n<td style=\"width: 16.6667%; background-color: #ffffff;\"><strong>6<\/strong><\/td>\n<td style=\"width: 16.6667%; background-color: #ffffff;\"><strong>12<\/strong><\/td>\n<td style=\"width: 16.6667%; background-color: #ffffff;\"><strong>18<\/strong><\/td>\n<td style=\"width: 16.6667%; background-color: #ffffff;\"><strong>24<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<th style=\"width: 16.6667%; height: 24px; background-color: #eeeeee; border: max(0.0694444vw, 1px) solid #b6bfbf;\"><span class=\"TextRun SCXW208998347 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW208998347 BCX0\">Shockwave <\/span><span class=\"NormalTextRun SCXW208998347 BCX0\">IVL<\/span><\/span><span class=\"EOP SCXW208998347 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/th>\n<td style=\"width: 16.6667%; height: 24px; background-color: #ffffff;\"><span class=\"TextRun SCXW53042425 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW53042425 BCX0\">131<\/span><\/span><span class=\"EOP SCXW53042425 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/td>\n<td style=\"width: 16.6667%; height: 24px; background-color: #ffffff;\">120<\/td>\n<td style=\"width: 16.6667%; height: 24px; background-color: #ffffff;\">107<\/td>\n<td style=\"width: 16.6667%; height: 24px; background-color: #ffffff;\">88<\/td>\n<td style=\"width: 16.6667%; height: 24px; background-color: #ffffff;\">83<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<th style=\"width: 16.6667%; height: 24px; background-color: #eeeeee; border: max(0.0694444vw, 1px) solid #b6bfbf;\"><span class=\"TextRun SCXW50867163 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW50867163 BCX0\">PTA<\/span><\/span><span class=\"EOP SCXW50867163 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/th>\n<td style=\"width: 16.6667%; height: 24px;\">136<\/td>\n<td style=\"width: 16.6667%; height: 24px;\">107<\/td>\n<td style=\"width: 16.6667%; height: 24px;\">95<\/td>\n<td style=\"width: 16.6667%; height: 24px;\">75<\/td>\n<td style=\"width: 16.6667%; height: 24px;\">66<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">*Primary patency defined as freedom from provisional stenting at index procedure, freedom from clinically-driven target lesion revascularization, and freedom from restenosis determined by duplex ultrasound.\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"conclusion\" class=\"block block--content-3-or-4-up text_colors \" aria-labelledby=\"section-heading-conclusion\">\n\t<div class=\"container\">\n\n\t\t<!-- Header -->\n\t\t\t\t\t<header class=\"heading-row\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"section-heading-conclusion\" class=\"optional-heading\">\n\t\t\t\t\t\tConclusion\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/header>\n\t\t\n\t\t<!-- Cards Section -->\n\t\t<ul class=\"cards three-cards\" role=\"list\">\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\"><\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">DISRUPT PAD III compared endovascular therapy of IVL to percutaneous transluminal angioplasty (PTA) for treatment of calcified peripheral arteries.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\"><\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Results validate Shockwave IVL as a safe and effective treatment for heavily calcified femoropopliteal lesions.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\"><\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Shockwave IVL provides superior vessel prep and excellent long-term results in calcified vessels while preserving future treatment options. <\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_e951d606712d906972dea95dc926e733\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 90px; --aboveMobile: 45px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_4bf6f52e46b5aaddbe90120134c75b04\" class=\"block block--attribution \" role=\"region\" aria-labelledby=\"block_4bf6f52e46b5aaddbe90120134c75b04-heading\" aria-describedby=\"block_4bf6f52e46b5aaddbe90120134c75b04-desc\">\n\t<div class=\"container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"block_4bf6f52e46b5aaddbe90120134c75b04-heading\" class=\"heading\">\n\t\t\t\t\tStudy Leadership\t\t\t\t<\/h3>\n\t\t\t\t\t\t<p id=\"block_4bf6f52e46b5aaddbe90120134c75b04-desc\" class=\"sr-only\">This section contains attributions including profile pictures, titles, descriptions, and Twitter handles.<\/p>\n\n\t\t\t\t\t\t\t<ul class=\"attributions-container\" role=\"list\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Gunnar Tepe, MD<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Professor of Radiology, Head of Diagnostic & Interventional Radiology, RoMed Clinic, Rosenheim, Germany<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Marianne Brodmann, MD<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Head of Division of Angiology, Medical University Graz, Graz, Austria<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">William Bachinsky, MD<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Cardiologist, Penn State Health Holy Spirit Medical Center, Mechanicsburg, PA<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Sahil. A Parikh, MD<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Associate Professor of Medicine, Columbia University, New York, NY<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"twitter-handle\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/twitter.com\/sahilparikhmd\" target=\"_blank\" rel=\"noopener noreferrer\">@sahilparikhmd<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">William A. Gray, MD<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Professor of Medicine, Main Line Health, Wynnewood, PA<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_de9313e4cdd8d51ffc068169a1687e88\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">Tepe et al Intravascular Lithotripsy for Peripheral Artery Calcification: Mid-term Outcomes From the Randomized Disrupt PAD III Trial. JSCAI, Volume 1, Issue 4, 100341.<br \/>\nTepe et al Intravascular Lithotripsy for Peripheral Artery Calcification 30-Day Outcomes From the Randomized Disrupt PAD III Trial JACC Cardiovasc Interv. 2021 Jun 28;14(12):1352-1361.<br \/>\n<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section id=\"block_40674eeb7529646d9a7bf14f2b715be4\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors \">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">More Clinical Evidence<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/?disease-state_terms%5B%5D=peripheral-artery-disease-de&amp;sort_order=date_desc&amp;pageNumber=1\" target=\"_self\" aria-label=\"Explore Peripheral Studies - link to page\">Explore Peripheral Studies<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/?disease-state_terms%5B%5D=peripheral-artery-disease-de&amp;sort_order=date_desc&amp;pageNumber=1\" target=\"_self\" aria-label=\"Explore Peripheral Studies - link to page\">Explore Peripheral Studies<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-13042\" aria-describedby=\"post-category-13042 post-excerpt-13042\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-13042\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/disrupt-btk-ii-clti-cohort-analysis\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT BTK II CLTI Cohort Analysis\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-13042\">\n\t\t\t\t\t\tThis DISRUPT BTK II sub-analysis focuses on results from the CLTI cohort at 12-months.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-13042\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6687\" aria-describedby=\"post-category-6687 post-excerpt-6687\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6687\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/btk-ii\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT BTK II\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6687\">\n\t\t\t\t\t\tGlobal prospective, multi-center, single-arm  study assessing the safety and effectiveness of Shockwave peripheral IVL in treating long, calcified BTK lesions. \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6687\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6528\" aria-describedby=\"post-category-6528 post-excerpt-6528\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6528\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/pad-iii-os\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Observational Study\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6528\">\n\t\t\t\t\t\tThe largest prospective real-world evidence for the treatment of complex, heavily calcified peripheral arterial disease (PAD).\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6528\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_43bebbe4bddb40903a49ac820d57a897\" class=\"block block--related-posts \" aria-labelledby=\"related-posts-title\">\n\t<div class=\"related-posts--title container\">\n\t\t<h2 id=\"related-posts-title\" class=\"text_colors\">From Our Education Library<\/h2>\n\t\t<div class=\"related-posts__btn-dots-wrap\">\n\t\t\t\n<a data-atom=\"button\" class=\"btn--secondary\" href=\"https:\/\/shockwavemedical.com\/de\/education\/?technology_terms%5B%5D=peripheral-ivl-de&amp;sort_order=date_desc&amp;pageNumber=1\" target=\"_self\" aria-label=\"Explore More - link to page\">Explore More<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t<div class=\"related-posts--dots cards_slider_dots\" aria-hidden=\"true\"><\/div>\n\t\t<\/div>\n\t<\/div>\n\n\t<ul class=\"related-posts-list cards_slider\" role=\"list\">\n\t\t\t\t\t\t<li class=\"related-posts-item card_slide\" role=\"listitem\">\n\t\t\t\t\t<figure class=\"related-posts-item--image\">\n\t\t\t\t\t\t<img decoding=\"async\" width=\"386\" height=\"540\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/02\/Dr-Saratzis-index-image.png\" class=\"attachment-full size-full wp-post-image lazyload\" alt=\"Shockwave IVL as First-line: The Real World Impact of the V-PAD Consensus\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/02\/Dr-Saratzis-index-image.png 386w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/02\/Dr-Saratzis-index-image-214x300.png 214w\" data-sizes=\"(max-width: 386px) 100vw, 386px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 386px; --smush-placeholder-aspect-ratio: 386\/540;\" \/>\t\t\t\t\t\t<div class=\"thumbnail-arrow\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t<i class=\"fa-regular fa-arrow-right\"><\/i>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/figure>\n\n\t\t\t\t\t<div class=\"related-posts-item--text-container\" id=\"post-title-13418\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/education\/real-world-impact-of-vpad-consensus-with-prof-thanos-saratzis\/\" class=\"related-posts-item--title\" aria-labelledby=\"post-title-13418\" aria-describedby=\"post-category-13418\">\n\t\t\t\t\t\t\tShockwave IVL as First-line: The Real World Impact of the V-PAD Consensus\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"related-posts-item--category\" id=\"post-category-13418\">\n\t\t\t\t\t\t<div class=\"tags\"><strong>Clinical Evidence<\/strong> <\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"related-posts-item card_slide\" role=\"listitem\">\n\t\t\t\t\t<figure class=\"related-posts-item--image\">\n\t\t\t\t\t\t<img decoding=\"async\" width=\"440\" height=\"570\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/09\/Javelin-Case-2-Images-01.png\" class=\"attachment-full size-full wp-post-image lazyload\" alt=\"Shockwave Javelin for below the ankle revascularization In a patient with CLTI\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/09\/Javelin-Case-2-Images-01.png 440w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/09\/Javelin-Case-2-Images-01-232x300.png 232w\" data-sizes=\"(max-width: 440px) 100vw, 440px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 440px; --smush-placeholder-aspect-ratio: 440\/570;\" \/>\t\t\t\t\t\t<div class=\"thumbnail-arrow\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t<i class=\"fa-regular fa-arrow-right\"><\/i>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/figure>\n\n\t\t\t\t\t<div class=\"related-posts-item--text-container\" id=\"post-title-12685\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/education\/shockwave-javelin-for-below-the-ankle-revascularization-in-a-patient-with-clti\/\" class=\"related-posts-item--title\" aria-labelledby=\"post-title-12685\" aria-describedby=\"post-category-12685\">\n\t\t\t\t\t\t\tShockwave Javelin for below the ankle revascularization In a patient with CLTI\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"related-posts-item--category\" id=\"post-category-12685\">\n\t\t\t\t\t\t<div class=\"tags\"><strong>Case Reviews<\/strong> <\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"related-posts-item card_slide\" role=\"listitem\">\n\t\t\t\t\t<figure class=\"related-posts-item--image\">\n\t\t\t\t\t\t<img decoding=\"async\" width=\"386\" height=\"540\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/03\/BTK-II-Acute-30-Day-Outcomes-Index-Image.png\" class=\"attachment-full size-full wp-post-image lazyload\" alt=\"DISRUPT BTK II Acute & 30-Day Outcomes with Dr. Venita Chandra and Dr. Ehrin Armstrong\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/03\/BTK-II-Acute-30-Day-Outcomes-Index-Image.png 386w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/03\/BTK-II-Acute-30-Day-Outcomes-Index-Image-214x300.png 214w\" data-sizes=\"(max-width: 386px) 100vw, 386px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 386px; --smush-placeholder-aspect-ratio: 386\/540;\" \/>\t\t\t\t\t\t<div class=\"thumbnail-arrow\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t<i class=\"fa-regular fa-arrow-right\"><\/i>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/figure>\n\n\t\t\t\t\t<div class=\"related-posts-item--text-container\" id=\"post-title-11944\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/education\/disrupt-btk-ii-acute-30-day-outcomes-with-dr-venita-chandra-and-dr-ehrin-armstrong\/\" class=\"related-posts-item--title\" aria-labelledby=\"post-title-11944\" aria-describedby=\"post-category-11944\">\n\t\t\t\t\t\t\tDISRUPT BTK II Acute & 30-Day Outcomes with Dr. Venita Chandra and Dr. Ehrin Armstrong\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"related-posts-item--category\" id=\"post-category-11944\">\n\t\t\t\t\t\t<div class=\"tags\"><strong>Clinical Evidence<\/strong> <\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"related-posts-item card_slide\" role=\"listitem\">\n\t\t\t\t\t<figure class=\"related-posts-item--image\">\n\t\t\t\t\t\t<img decoding=\"async\" width=\"386\" height=\"540\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/03\/BTK-II-Acute-Outcomes-Index-Image.png\" class=\"attachment-full size-full wp-post-image lazyload\" alt=\"DISRUPT BTK II Acute Outcomes: Physician Perspectives with Prof. Holden & Dr. Lakshminarayan\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/03\/BTK-II-Acute-Outcomes-Index-Image.png 386w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/03\/BTK-II-Acute-Outcomes-Index-Image-214x300.png 214w\" data-sizes=\"(max-width: 386px) 100vw, 386px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 386px; --smush-placeholder-aspect-ratio: 386\/540;\" \/>\t\t\t\t\t\t<div class=\"thumbnail-arrow\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t<i class=\"fa-regular fa-arrow-right\"><\/i>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/figure>\n\n\t\t\t\t\t<div class=\"related-posts-item--text-container\" id=\"post-title-11936\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/education\/disrupt-btk-ii-acute-outcomes-physician-perspectives-with-prof-holden-dr-lakshminarayan\/\" class=\"related-posts-item--title\" aria-labelledby=\"post-title-11936\" aria-describedby=\"post-category-11936\">\n\t\t\t\t\t\t\tDISRUPT BTK II Acute Outcomes: Physician Perspectives with Prof. Holden & Dr. Lakshminarayan\t\t\t\t\t\t<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"related-posts-item--category\" id=\"post-category-11936\">\n\t\t\t\t\t\t<div class=\"tags\"><strong>Clinical Evidence<\/strong> <\/div>\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>The largest-ever randomized clinical study of Shockwave peripheral IVL treatment in severely calcified peripheral lesions, out to 24 months.<\/p>\n","protected":false},"featured_media":3976,"template":"","format":[],"meta":{"_acf_changed":true,"content-type":""},"disease-state":[145,169],"product-tag":[285],"specialty":[297,330,334,338,346],"technology":[326],"class_list":["post-6555","clinical-evidence","type-clinical-evidence","status-publish","has-post-thumbnail","hentry","disease-state-above-the-knee-atk-de","disease-state-peripheral-artery-disease-de","product-tag-shockwave-m5-de","specialty-fellows-residents-de","specialty-interventional-cardiologists-de","specialty-interventional-radiologists-de","specialty-nurses-technologists-de","specialty-vascular-surgeons-de","technology-peripheral-ivl-de"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/clinical-evidence\/6555","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/clinical-evidence"}],"about":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/types\/clinical-evidence"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media\/3976"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media?parent=6555"}],"wp:term":[{"taxonomy":"disease-state","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/disease-state?post=6555"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/format?post=6555"},{"taxonomy":"product-tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/product-tag?post=6555"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/specialty?post=6555"},{"taxonomy":"technology","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/technology?post=6555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}