{"id":6594,"date":"2018-11-25T15:44:00","date_gmt":"2018-11-25T21:44:00","guid":{"rendered":"https:\/\/shockwavemedical.com\/clinical-evidence\/disrupt-pad-ii\/"},"modified":"2024-12-23T11:42:41","modified_gmt":"2024-12-23T17:42:41","slug":"pad-ii","status":"publish","type":"clinical-evidence","link":"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/pad-ii\/","title":{"rendered":"DISRUPT PAD II"},"content":{"rendered":"\n<section id=\"block_dbe17a3c37fd22f63aa0500f72a1736f\" class=\"block block--primary-header u-darkMode u-bgColor_primary\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Background-Pulses.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">DISRUPT PAD II <\/h1>\n\t\t\t<h3 class=\"sub-heading\">Core lab adjudicated, long-term, multi-center study exclusively enrolling heavily calcified lesions building upon DISRUPT PAD I. Designed to assess the safety and performance of Shockwave IVL as stand-alone treatment among eight centers in Europe and New Zealand in 2015.\u00a0<\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/DISRUPT-PAD-II-Clinical-Hero-Image-3.png\" alt=\"DISRUPT PAD II logo\" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t\t\t<div class=\"mobile-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Clinical-Hero-Images-mobile-10.png\" alt=\"DISRUPT PAD II logo\" role=\"img\" aria-label=\"Foreground image for mobile\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 814px; --smush-placeholder-aspect-ratio: 814\/412;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_f9e675a38de0f107c3affa902c02f692\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_e43301d7f041d2c9553237989a4444a5\" class=\"block block--attribution \" role=\"region\" aria-labelledby=\"block_e43301d7f041d2c9553237989a4444a5-heading\" aria-describedby=\"block_e43301d7f041d2c9553237989a4444a5-desc\">\n\t<div class=\"container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"block_e43301d7f041d2c9553237989a4444a5-heading\" class=\"heading\">\n\t\t\t\t\tStudy Leadership \t\t\t\t<\/h3>\n\t\t\t\t\t\t<p id=\"block_e43301d7f041d2c9553237989a4444a5-desc\" class=\"sr-only\">This section contains attributions including profile pictures, titles, descriptions, and Twitter handles.<\/p>\n\n\t\t\t\t\t\t\t<ul class=\"attributions-container\" role=\"list\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Marianne Brodmann, MD  <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Co-Principal Investigator  \r\nDivision of Internal Medicine Medical University Graz, Graz, Austria         <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Thomas Zeller, MD\u00a0<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Co-Principal Investigator  \r\nUniversit\u00e4ts-Herz-Zentrum Freiburg-Bad Krozingen, Bad  \r\nKrozingen, Germany         <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_f9e675a38de0f107c3affa902c02f692\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_c8f3b4e925fce888d323242f452d2259\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2><span class=\"TextRun SCXW120995252 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun CommentStart SCXW120995252 BCX0\">PAD II<\/span><span class=\"NormalTextRun SCXW120995252 BCX0\"> Study Details<\/span><\/span><span class=\"EOP SCXW120995252 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/h2>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-0\" role=\"listitem\" aria-labelledby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-0-number\" aria-describedby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-0-number\">60<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-0-description\">\n\t\t\t\t\t\tPatients with heavily calcified femoral-popliteal lesions\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-1\" role=\"listitem\" aria-labelledby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-1-number\" aria-describedby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-1-number\">85<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-1-description\">\n\t\t\t\t\t\tSevere calcification by PARC\u00b9\u2020\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-2\" role=\"listitem\" aria-labelledby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-2-number\" aria-describedby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-2-number\">98<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>\u00a0mm<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-2-description\">\n\t\t\t\t\t\tAverage calcified length\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-3\" role=\"listitem\" aria-labelledby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-3-number\" aria-describedby=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-3-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-3-number\">12<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_9d2ec24e13b4cdaec23ba45a763e52f7-card-3-description\">\n\t\t\t\t\t\tMonth follow-up\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_fdf4164e81564a8d4f47854d235792a4\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">1: Brodmann M et al, Primary outcomes and mechanism of action of Intravascular Lithotripsy in calcified, femoropopliteal lesions: Results of DISRUPT PAD II, Catheter Cardiovasc Interv. 2018<br \/>\n\u2020PARC: Peripheral Academic Research Consortium<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_f9e675a38de0f107c3affa902c02f692\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_e4890322a822b7bc948ad54519bed405\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Compelling Safety & Performance in Severely Calcified Lesions*<\/h2>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_0faaff3e90c48ccb6baf7c9e162d9140\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-0\" role=\"listitem\" aria-labelledby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-0-number\" aria-describedby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-0-number\">0<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-0-description\">\n\t\t\t\t\t\tPerforations, embolization, thrombus, no reflow, abrupt closure\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-1\" role=\"listitem\" aria-labelledby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-1-number\" aria-describedby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-1-number\">1.7<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-1-description\">\n\t\t\t\t\t\tDissection (D\/E\/F)**, provisional stenting\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-2\" role=\"listitem\" aria-labelledby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-2-number\" aria-describedby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-2-number\">24<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-2-description\">\n\t\t\t\t\t\tResidual stenosis with average acute gain of 3.0 mm, average balloon inflation pressure of 6 atm after Shockwave IVL therapy\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-3\" role=\"listitem\" aria-labelledby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-3-number\" aria-describedby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-3-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-3-number\">100<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-3-description\">\n\t\t\t\t\t\tProcedural success, low use of adjunctive tools\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-4\" role=\"listitem\" aria-labelledby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-4-number\" aria-describedby=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-4-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-4-number\">79<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_0faaff3e90c48ccb6baf7c9e162d9140-card-4-description\">\n\t\t\t\t\t\tFreedom from clinically-driven target lesion revascularization\u202f(CD-TLR) at one year, with simple revascularization procedures\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_0c658bf31e60beea49cfc5a92877e2e0\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">*Core Lab and Clinidal Events Committee (CEC) adjudicated<br \/>\n**Guidewire induced through recanalization of a chronic total occlusion resolved with stent placement\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_f9e675a38de0f107c3affa902c02f692\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_51b6cee3447e9cdc3faf3ce0dbe2a168\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2><span class=\"TextRun SCXW208493116 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW208493116 BCX0\">Patients <\/span><span class=\"NormalTextRun SCXW208493116 BCX0\">Who Were Treated with Optimal Technique Had Less Than 9% <\/span><span class=\"NormalTextRun SCXW208493116 BCX0\">CD<\/span><span class=\"NormalTextRun SCXW208493116 BCX0\">\u2013<\/span><span class=\"NormalTextRun SCXW208493116 BCX0\">TLR <\/span><span class=\"NormalTextRun SCXW208493116 BCX0\">At 12-Months<\/span><\/span><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-6575 lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_1-1024x341.png\" alt=\"Bar chart displaying improved primary patency and CD-TLR rates with optimal technique. \" width=\"1200\" height=\"400\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_1-1024x341.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_1-300x100.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_1-768x256.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_1-1536x511.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_1.png 2000w\" data-sizes=\"(max-width: 1200px) 100vw, 1200px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1200px; --smush-placeholder-aspect-ratio: 1200\/400;\" \/><\/p>\n<p>\u00a0<\/p>\n<h2><span class=\"TextRun SCXW182919789 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW182919789 BCX0\">Balloon <\/span><span class=\"NormalTextRun SCXW182919789 BCX0\">Sizing and Therapeutic Overlap Enables Optimal Energy Delivery to <\/span><span class=\"NormalTextRun SCXW182919789 BCX0\">Peripheral <\/span><span class=\"NormalTextRun SCXW182919789 BCX0\">Calcified Lesions<\/span><\/span><span class=\"EOP SCXW182919789 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-6580 lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_2-1024x319.png\" alt=\"Illustration showing optimal vs. undersized balloon sizing and coverage. The left side depicts an 'Optimal' balloon fully apposed to the vessel wall, improving energy transfer, while an 'Undersized' balloon shows gaps, reducing efficiency.\" width=\"1200\" height=\"374\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_2-1024x319.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_2-300x94.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_2-768x240.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_2-1536x479.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Disrupt_PAD_II_Global_White_2.png 2000w\" data-sizes=\"(max-width: 1200px) 100vw, 1200px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1200px; --smush-placeholder-aspect-ratio: 1200\/374;\" \/><\/p>\n\t<\/div>\n\t<\/section>\n\n<section id=\"block_4db136f13295dbe40b621b4e88cfc6c2\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors \">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">More Shockwave Peripheral IVL Studies <\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6687\" aria-describedby=\"post-category-6687 post-excerpt-6687\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6687\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/btk-ii\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT BTK II\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6687\">\n\t\t\t\t\t\tGlobal prospective, multi-center, single-arm  study assessing the safety and effectiveness of Shockwave peripheral IVL in treating long, calcified BTK lesions. \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6687\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6555\" aria-describedby=\"post-category-6555 post-excerpt-6555\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6555\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/pad-iii-rct\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Randomized Clinical Trial\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6555\">\n\t\t\t\t\t\tThe largest-ever randomized clinical study of Shockwave peripheral IVL treatment in severely calcified peripheral lesions, out to 24 months.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6555\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6528\" aria-describedby=\"post-category-6528 post-excerpt-6528\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6528\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/pad-iii-os\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Observational Study\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6528\">\n\t\t\t\t\t\tThe largest prospective real-world evidence for the treatment of complex, heavily calcified peripheral arterial disease (PAD).\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6528\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>\n\n\n<section\n\tid=\"block_f9e675a38de0f107c3affa902c02f692\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Core lab adjudicated, long-term, multi-center study exclusively enrolling heavily calcified lesions building upon DISRUPT PAD I.<\/p>\n","protected":false},"featured_media":3986,"template":"","format":[],"meta":{"_acf_changed":true,"content-type":""},"disease-state":[145,153,169],"product-tag":[285],"specialty":[297,330,334,338,346],"technology":[326],"class_list":["post-6594","clinical-evidence","type-clinical-evidence","status-publish","has-post-thumbnail","hentry","disease-state-above-the-knee-atk-de","disease-state-below-the-knee-btk-de","disease-state-peripheral-artery-disease-de","product-tag-shockwave-m5-de","specialty-fellows-residents-de","specialty-interventional-cardiologists-de","specialty-interventional-radiologists-de","specialty-nurses-technologists-de","specialty-vascular-surgeons-de","technology-peripheral-ivl-de"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/clinical-evidence\/6594","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/clinical-evidence"}],"about":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/types\/clinical-evidence"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media\/3986"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media?parent=6594"}],"wp:term":[{"taxonomy":"disease-state","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/disease-state?post=6594"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/format?post=6594"},{"taxonomy":"product-tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/product-tag?post=6594"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/specialty?post=6594"},{"taxonomy":"technology","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/technology?post=6594"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}