{"id":8049,"date":"2024-11-01T15:47:04","date_gmt":"2024-11-01T20:47:04","guid":{"rendered":"https:\/\/shockwavemedical.com\/clinical-evidence\/empower-cad\/"},"modified":"2026-03-10T10:58:21","modified_gmt":"2026-03-10T15:58:21","slug":"empower-cad","status":"publish","type":"clinical-evidence","link":"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/empower-cad\/","title":{"rendered":"EMPOWER CAD"},"content":{"rendered":"\n\n\n<section id=\"block_52b9b69e485a1040f8794e4301bcea8b\" class=\"block block--primary-header u-darkMode u-bgColor_primary\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Background-Pulses.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">EMPOWER CAD<\/h1>\n\t\t\t<h3 class=\"sub-heading\">The first prospective, multi-center, single-arm, all-female, all-comers study to generate real-world clinical evidence associated with an IVL-first* treatment strategy in a patient population with calcified coronary artery disease (CAD).<sup>1<\/sup><\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/EMPOWER-CAD-clinical-hero-image-4.png\" alt=\"EMPOWER CAD logo\" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t\t\t<div class=\"mobile-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Clinical-Hero-Images-mobile-06.png\" alt=\"Empower CAD logo\" role=\"img\" aria-label=\"Foreground image for mobile\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 814px; --smush-placeholder-aspect-ratio: 814\/360;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_4f0daf48e34c5c1628830f1e8a153ba5\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_3cc69c10eb84ba3347194885d16ef84e\" class=\"block block--attribution \" role=\"region\" aria-labelledby=\"block_3cc69c10eb84ba3347194885d16ef84e-heading\" aria-describedby=\"block_3cc69c10eb84ba3347194885d16ef84e-desc\">\n\t<div class=\"container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"block_3cc69c10eb84ba3347194885d16ef84e-heading\" class=\"heading\">\n\t\t\t\t\tStudy leadership\t\t\t\t<\/h3>\n\t\t\t\t\t\t<p id=\"block_3cc69c10eb84ba3347194885d16ef84e-desc\" class=\"sr-only\">This section contains attributions including profile pictures, titles, descriptions, and Twitter handles.<\/p>\n\n\t\t\t\t\t\t\t<ul class=\"attributions-container\" role=\"list\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"profile-picture\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/04\/Margaret-McEntegart-headshot.png\" alt=\"Dr. Margaret McEntegart headshot\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 157px; --smush-placeholder-aspect-ratio: 157\/157;\" \/>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Margaret McEntegart, MD, PhD <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Director of Complex Percutaneous Coronary Intervention Program \r\nColumbia University Medical Center\/New York-Presbyterian Hospital <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"profile-picture\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/04\/Alexandra-Lansky-headshot.jpg\" alt=\"Dr. Alexandra Lansky headshot\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 157px; --smush-placeholder-aspect-ratio: 157\/157;\" \/>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Alexandra Lansky, MD, FACC, FAHA, FSCAI, FESC <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Professor of Medicine, Section of Cardiovascular Medicine and Director, Heart and Vascular Clinical Research Program \r\nYale University School of Medicine <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"profile-picture\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/04\/Nieves-Gonzalo-headshot.jpg\" alt=\"Dr. Nieves Gonzalo headshot\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 157px; --smush-placeholder-aspect-ratio: 157\/157;\" \/>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Nieves Gonzalo, MD, PhD<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Consultant Interventional Cardiologist \r\nHospital Clinico San Carlos, Madrid, Spain <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_f8bbd72b68300395240e06ce47f5c297\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">Drs. McEntegart, Lansky and Gonzalo are paid consultants of Shockwave Medical.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_18800c66d31e44357788dbda113b1df2\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>EMPOWER CAD Study Design<\/h2>\n\t<\/div>\n\t<\/section>\n\n\n<!-- BLOCK CONTENT -->\n<section id=\"block_fb3d090ebc30dce98719422ae04ce8f1\"  class=\"block block--section \">\n\t<div class=\"container\">\n\t\t\n\n<section id=\"block_abe21d68e61f11c7a5e061f286ed713c\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-0\" role=\"listitem\" aria-labelledby=\"block_abe21d68e61f11c7a5e061f286ed713c-card-0-number\" aria-describedby=\"block_abe21d68e61f11c7a5e061f286ed713c-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-0-number\">399<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-0-description\">\n\t\t\t\t\t\tPatients\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-1\" role=\"listitem\" aria-labelledby=\"block_abe21d68e61f11c7a5e061f286ed713c-card-1-number\" aria-describedby=\"block_abe21d68e61f11c7a5e061f286ed713c-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-1-number\">103<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-1-description\">\n\t\t\t\t\t\tPatient OCT sub study\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-2\" role=\"listitem\" aria-labelledby=\"block_abe21d68e61f11c7a5e061f286ed713c-card-2-number\" aria-describedby=\"block_abe21d68e61f11c7a5e061f286ed713c-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-2-number\">45<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_abe21d68e61f11c7a5e061f286ed713c-card-2-description\">\n\t\t\t\t\t\tGlobal sites\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"design\" class=\"block block--study-design-patient-chars shockwave\" role=\"region\" aria-labelledby=\"design-heading\">\n\t<div class=\"container\">\n\t\t\t\t<div class=\"columns wysiwyg_styles\" aria-label=\"Study Design Columns\">\n\t\t\t<div class=\"columns-2-and-3\">\n\t\t\t\t<div class=\"column-2\">\n\t\t\t\t\t<p><strong>Objective<\/strong><\/p>\n<p>Prospective, multi-center, single-arm used to generate real-world clinical evidence for coronary IVL in a population of female patients with calcified CAD.<\/p>\n<p><strong>Key Inclusion Criteria<\/strong><\/p>\n<ul>\n<li>Nonpregnant female aged 18 years or older<\/li>\n<li>Meets indications for percutaneous coronary intervention (PCI) and stent<\/li>\n<li>Scheduled to undergo PCI with coronary IVL & stenting per standard of care for non-stented lesion<\/li>\n<\/ul>\n<p><strong>Key Exclusion Criteria<\/strong><\/p>\n<ul>\n<li>Patients with in-stent restenosis<\/li>\n<li>Patients actively in cardiogenic shock<\/li>\n<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-3\">\n\t\t\t\t\t<p><strong>Primary Safety Endpoint<\/strong><\/p>\n<p>Target lesion failure (TLF) defined as a composite of cardiac death, myocardial Infarction (per fourth universal definition) attributable to target vessel (TV-MI), or ischemia-driven target lesion revascularization (ID-TLR) at 30 days.<\/p>\n<p><strong>Primary Effectiveness Endpoint<\/strong><\/p>\n<p>Procedure success defined as stent delivery with a residual in-stent stenosis \u226430% in all target lesions (core laboratory assessed) and without in-hospital TLF (CEC adjudicated).<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"column-1\">\n\t\t\t\t<div class=\"column-1-content\">\n\t\t\t\t\t<div class=\"column-1-content-top\">\n\t\t\t\t\t\tThis all-comers study was designed to include female patients who have severely calcified coronary artery disease \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"column-1-content-bottom\">\n\t\t\t\t\t\tPatients followed up to 30 days, 1 year, 2 years & 3 years\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-1-arrow\" aria-hidden=\"true\" aria-label=\"Arrow pointing downwards to indicate result\"><i class=\"fa-regular fa-arrow-down\"><\/i><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_37997b04d3c144c21b812b5ce7d374e6\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 90px; --aboveMobile: 45px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"why\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>The Growing Need to EMPOWER<\/h2>\n<p><strong>Underdiagnosed. Underrepresented. Underwhelming outcomes.<\/strong> Coronary artery disease in female patients has historically been under investigated in the clinical setting. The rationale for exclusion was based on females being a more high-risk patient population and presenting with atypical symptoms. This, coupled with more tortuous anatomy and complex plaque patterns, frequently leads to worse outcomes.<sup>2, 3, 5<\/sup><\/p>\n\t<\/div>\n\t<\/section>\n\n\n<section\n\tid=\"block_b834911dce9d099296de9005a7237038\"\n\tclass=\"block block--testimonial text_colors \"\n\taria-labelledby=\"testimonial-title-block_b834911dce9d099296de9005a7237038\">\n\t<div class=\"container\">\n\t\t<div class=\"quote-and-image\">\n\t\t\t<div class=\"quote-and-author\">\n\t\t\t\t<h2 id=\"testimonial-title-block_b834911dce9d099296de9005a7237038\" class=\"sr-only\">Testimonial<\/h2> <!-- Visually hidden heading for accessibility -->\n\n\t\t\t\t\t\t\t\t\t<blockquote class=\"quote\">\n\t\t\t\t\t\t<div class=\"quote-quotation-symbol\" aria-hidden=\"true\">\u201c<\/div>\n\t\t\t\t\t\t<div class=\"quote-quotation-text\">\n\t\t\t\t\t\t\t<p>Previous reports with atherectomy have shown that females with calcified CAD are more susceptible to adverse procedural outcomes compared to males. Despite often being more challenging to treat, female patients are under-represented in published data, and there have been no dedicated prospective studies performed on this population. EMPOWER CAD will be an extremely valuable study to better inform interventional cardiologists on the optimal treatment strategy for these complex patients. <\/p>\n\t\t\t\t\t\t\t<div class=\"author-and-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"author\">\n\t\t\t\t\t\t\t\t\t\tDr. Margaret McEntegart\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/blockquote>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"importance\" class=\"block block--youtube-video-with-text-overlay text_colors \">\n\t<div class=\"block__container\">\n\t\t<div class=\"thumbnail\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/09\/The-Importance-of-EMPOWER-CAD_thumbnail.jpg\" alt=\"The Importance of EMPOWER CAD\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<div class=\"play-button-container\">\n\t\t\t\t<button type=\"button\" aria-label=\"Play video\" class=\"play-button btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-solid fa-play\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t<!-- Heading, description, and button -->\n\t\t<div class=\"heading-description-button\">\n\t\t\t\t\t\t\t<h2 class=\"heading\">\n\t\t\t\t\tThe Importance of EMPOWER CAD\t\t\t\t<\/h2>\n\t\t\t\n\t\t\t\t\t\t\t<p class=\"description\">\n\t\t\t\t\tIt\u2019s Time to EMPOWER: Real-World Data in All-Comer Patient Population. Watch as Dr. Margaret McEntegart and Dr. Alexandra Lansky discuss the importance of Shockwave IVL in a complex real-world, female-only patient population with EMPOWER CAD.\t\t\t\t<\/p>\n\t\t\t\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div class=\"video-modal\" role=\"dialog\" aria-modal=\"true\" aria-labelledby=\"modal-title-importance\" style=\"display: none;\">\n\t\t\t\t<button type=\"button\" aria-label=\"Close modal\" class=\"modal-close btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-xmark\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t\t<div class=\"modal-content\">\n\t\t\t\t\t<h2 id=\"modal-title-importance\" class=\"sr-only\">Video Player<\/h2>\n\t\t\t\t\t<lite-youtube videoid=\"5jCc3DkecFo\" style=\"width: 100%; height: 100%;\" title=\"The Importance of EMPOWER CAD\"><\/lite-youtube>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_f151984348adb9b0c9a756efef84968b\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>EMPOWER CAD is the first study to utilize \u200ban IVL-first* Strategy\u200b<\/h2>\n<p>EMPOWER CAD is the first coronary, all-comers Shockwave-sponsored study to implement an IVL-first* treatment algorithm. The DISRUPT CAD Pooled analysis suggested that an \u200bIVL-first* approach can potentially bridge the disparity in clinical outcomes between the genders<sup>4<\/sup>. In the EMPOWER \u200bstudy over 90% of lesions were treated with an IVL-first* treatment algorithm.\u200b<\/p>\n\t<\/div>\n\t\t\t<div class=\"button-container\">\n\t\t\t\t\t<\/div>\n\t<\/section>\n\n\n<section\n\tid=\"block_fae4b584514d8fc68d50973586abf393\"\n\tclass=\"block block--testimonial text_colors \"\n\taria-labelledby=\"testimonial-title-block_fae4b584514d8fc68d50973586abf393\">\n\t<div class=\"container\">\n\t\t<div class=\"quote-and-image\">\n\t\t\t<div class=\"quote-and-author\">\n\t\t\t\t<h2 id=\"testimonial-title-block_fae4b584514d8fc68d50973586abf393\" class=\"sr-only\">Testimonial<\/h2> <!-- Visually hidden heading for accessibility -->\n\n\t\t\t\t\t\t\t\t\t<blockquote class=\"quote\">\n\t\t\t\t\t\t<div class=\"quote-quotation-symbol\" aria-hidden=\"true\">\u201c<\/div>\n\t\t\t\t\t\t<div class=\"quote-quotation-text\">\n\t\t\t\t\t\t\t<p>Information that will be gathered in EMPOWER CAD will be immensely valuable, as it will provide more robust data with longer-term outcomes in a larger, all-comers patient cohort to determine whether Shockwave coronary IVL should be considered the front-line calcium modification approach in female patients.<\/p>\n\t\t\t\t\t\t\t<div class=\"author-and-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"author\">\n\t\t\t\t\t\t\t\t\t\tDr. Alexandra Lansky\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/blockquote>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_6372cc513f1491f36bff86d51bc03a8d\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><img decoding=\"async\" class=\"aligncenter wp-image-12222 size-large lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/EMPOWER-CAD-algorithm-chart-Updated-5-16-1024x753.png\" alt=\"Graphic outlining a Shockwave IVL-first algorithm for treating coronary artery disease.\" width=\"1024\" height=\"753\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/EMPOWER-CAD-algorithm-chart-Updated-5-16-1024x753.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/EMPOWER-CAD-algorithm-chart-Updated-5-16-300x221.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/EMPOWER-CAD-algorithm-chart-Updated-5-16-768x565.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/EMPOWER-CAD-algorithm-chart-Updated-5-16-1536x1130.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/EMPOWER-CAD-algorithm-chart-Updated-5-16.png 2000w\" data-sizes=\"(max-width: 1024px) 100vw, 1024px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1024px; --smush-placeholder-aspect-ratio: 1024\/753;\" \/><\/p>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_f1b2cad482cf85434dc0b3840d269a56\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Actuals<\/h2>\n\t<\/div>\n\t<\/section>\n\n\n<!-- BLOCK CONTENT -->\n<section id=\"block_fb3d090ebc30dce98719422ae04ce8f1\"  class=\"block block--section \">\n\t<div class=\"container\">\n\t\t\n\n<section id=\"block_3ebb86e8b1eb9c1f608478bfcb7fd6ff\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3><strong>Enrollment<\/strong><\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_41fe80ba5fb273103deef8e39c782395\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_41fe80ba5fb273103deef8e39c782395-card-0\" role=\"listitem\" aria-labelledby=\"block_41fe80ba5fb273103deef8e39c782395-card-0-number\" aria-describedby=\"block_41fe80ba5fb273103deef8e39c782395-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_41fe80ba5fb273103deef8e39c782395-card-0-number\">399<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_41fe80ba5fb273103deef8e39c782395-card-0-description\">\n\t\t\t\t\t\tPatients\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_41fe80ba5fb273103deef8e39c782395-card-1\" role=\"listitem\" aria-labelledby=\"block_41fe80ba5fb273103deef8e39c782395-card-1-number\" aria-describedby=\"block_41fe80ba5fb273103deef8e39c782395-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_41fe80ba5fb273103deef8e39c782395-card-1-number\">449<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_41fe80ba5fb273103deef8e39c782395-card-1-description\">\n\t\t\t\t\t\tSite Reported Target Lesions Treated**\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_ee4f58e6a85459905e9f3588fa253ef3\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3><strong>Pre-Shockwave IVL<\/strong><\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_27fe585a95e6803a3d672ddc01831061\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-0\" role=\"listitem\" aria-labelledby=\"block_27fe585a95e6803a3d672ddc01831061-card-0-number\" aria-describedby=\"block_27fe585a95e6803a3d672ddc01831061-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-0-number\">2.0<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-0-description\">\n\t\t\t\t\t\tCutting\/scoring balloon\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-1\" role=\"listitem\" aria-labelledby=\"block_27fe585a95e6803a3d672ddc01831061-card-1-number\" aria-describedby=\"block_27fe585a95e6803a3d672ddc01831061-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-1-number\">68.4<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-1-description\">\n\t\t\t\t\t\tDilatation\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-2\" role=\"listitem\" aria-labelledby=\"block_27fe585a95e6803a3d672ddc01831061-card-2-number\" aria-describedby=\"block_27fe585a95e6803a3d672ddc01831061-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-2-number\">7.3<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_27fe585a95e6803a3d672ddc01831061-card-2-description\">\n\t\t\t\t\t\tAtherectomy\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_0ce2289248a643006a13704f243b1e6a\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3><strong>Shockwave IVL<\/strong><\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_8f3c4575e405b2ba3d560d45f22c2af0\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_8f3c4575e405b2ba3d560d45f22c2af0-card-0\" role=\"listitem\" aria-labelledby=\"block_8f3c4575e405b2ba3d560d45f22c2af0-card-0-number\" aria-describedby=\"block_8f3c4575e405b2ba3d560d45f22c2af0-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_8f3c4575e405b2ba3d560d45f22c2af0-card-0-number\">90.6<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_8f3c4575e405b2ba3d560d45f22c2af0-card-0-description\">\n\t\t\t\t\t\tIVL-first approach\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_ab89fd46bc96ee135a0de702de31af3f\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3><strong>Stenting<\/strong><\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_c08c34b0615e7dfdc29c162bc2574560\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_c08c34b0615e7dfdc29c162bc2574560-card-0\" role=\"listitem\" aria-labelledby=\"block_c08c34b0615e7dfdc29c162bc2574560-card-0-number\" aria-describedby=\"block_c08c34b0615e7dfdc29c162bc2574560-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_c08c34b0615e7dfdc29c162bc2574560-card-0-number\">98.4<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_c08c34b0615e7dfdc29c162bc2574560-card-0-description\">\n\t\t\t\t\t\tStent implanted\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_9ee5cd9cec727b082547f758ce31ef0d\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3><strong>Post-stent<\/strong><\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_0400a3360a8c11df902bba80fce8768e\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_0400a3360a8c11df902bba80fce8768e-card-0\" role=\"listitem\" aria-labelledby=\"block_0400a3360a8c11df902bba80fce8768e-card-0-number\" aria-describedby=\"block_0400a3360a8c11df902bba80fce8768e-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_0400a3360a8c11df902bba80fce8768e-card-0-number\">91.9<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_0400a3360a8c11df902bba80fce8768e-card-0-description\">\n\t\t\t\t\t\tDilatation\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_d59c504206152d8732a7c4f3a6212abd\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>High-risk, complex real-world patient cohort<\/h2>\n<p>\u00a0<\/p>\n\t<\/div>\n\t<\/section>\n\n\n<!-- BLOCK CONTENT -->\n<section id=\"block_fb3d090ebc30dce98719422ae04ce8f1\"  class=\"block block--section \">\n\t<div class=\"container\">\n\t\t\n\n<section id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-0\" role=\"listitem\" aria-labelledby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-0-number\" aria-describedby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-0-number\">32<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-0-description\">\n\t\t\t\t\t\tPrior myocardial infarction\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-1\" role=\"listitem\" aria-labelledby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-1-number\" aria-describedby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-1-number\">26<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-1-description\">\n\t\t\t\t\t\tAcute coronary syndrome\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-2\" role=\"listitem\" aria-labelledby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-2-number\" aria-describedby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-2-number\">28<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-2-description\">\n\t\t\t\t\t\tChronic kidney disease\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-3\" role=\"listitem\" aria-labelledby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-3-number\" aria-describedby=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-3-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-3-number\">37<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_6c8889dfb041f4c3b1e3462f637cbe0d-card-3-description\">\n\t\t\t\t\t\tBifurcation and trifurcation lesions\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_2f8528cd3e3aaf945076df09b7ef5c24\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Effectiveness Endpoint<\/h2>\n<p>Shockwave IVL proved to be an effective calcium modification strategy in an all-comers female population\u200b.<\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 96px;\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px;\">Procedural success<\/td>\n<td style=\"width: 50%; height: 24px;\">87.4%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px;\">Stent delivered<\/td>\n<td style=\"width: 50%; height: 24px;\">98.5%<sup>7<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px;\">\u2264 30% residual stenosis<\/td>\n<td style=\"width: 50%; height: 24px;\">98.5%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px;\">Without in-hospital TLF<\/td>\n<td style=\"width: 50%; height: 24px;\">89.2%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-12230 size-large lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/Effectiveness-Endpoints-1024x306.png\" alt=\"graphs comparing Effectiveness Endpoints\" width=\"1024\" height=\"306\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/Effectiveness-Endpoints-1024x306.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/Effectiveness-Endpoints-300x90.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/Effectiveness-Endpoints-768x229.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/Effectiveness-Endpoints-1536x458.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/05\/Effectiveness-Endpoints.png 2000w\" data-sizes=\"(max-width: 1024px) 100vw, 1024px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1024px; --smush-placeholder-aspect-ratio: 1024\/306;\" \/><\/p>\n<p>\u00a0<\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"primary-safety\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Primary Safety Endpoint<\/h2>\n<p>In a real-world female patient population with challenging calcium Shockwave IVL had strong safety outcomes.<\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 113px;\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.4236%; height: 24px; text-align: center;\">Parameter<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">Rate<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.4236%; height: 24px; text-align: left;\"><strong>Target lesion failure within 30-days<\/strong><\/td>\n<td style=\"width: 33.3333%; height: 24px;\"><strong>11.6%<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.4236%; height: 24px; text-align: left;\">Cardiac death<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">1.0%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.4236%; height: 17px; text-align: left;\">MI<\/p>\n<p style=\"margin-left: 20px;\">Peri-procedural MI (<48hrs)<\/p>\n<p style=\"margin-left: 20px;\">Spontaneous MI (>48hrs)<\/p>\n<\/td>\n<td style=\"width: 33.3333%; height: 17px;\">10.6%<br \/>\n9.6%<br \/>\n1.5%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 33.4236%; height: 24px; text-align: left;\">ID-TLR<\/td>\n<td style=\"width: 33.3333%; height: 24px;\">1.3%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<p>SCAI definition used for periprocedural MI. The Fourth Universal definition (Type 4a) used for spontaneous MI beyond discharge.<\/p>\n<ul>\n<li>Protocol required systematic biomarker collection in all patients.<\/li>\n<li>MI rate reflective of complex patient population<\/li>\n<li>Majority of MIs were biomarker elevation alone without clinical symptoms<\/li>\n<\/ul>\n\t<\/div>\n\t\t\t<div class=\"button-container\">\n\t\t\t\t\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_4f0daf48e34c5c1628830f1e8a153ba5\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_0a72bd91e2a47bd70c89229006d5542c\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Angiographic Complications<\/h2>\n<p>IVL has been proven to have consistently low angiographic complications across both male and female patients.<sup>6<\/sup><\/p>\n<h3>EMPOWER CAD<\/h3>\n<ul>\n<li>0.2% (1\/420) serious angiographic complication at final<\/li>\n<li>All complications were resolved at final imaging without further clinical sequelae<\/li>\n<\/ul>\n<table style=\"border-collapse: collapse; width: 100%; height: 192px;\">\n<tbody>\n<tr style=\"height: 48px;\">\n<td style=\"width: 20%; height: 48px;\">Parameter<\/td>\n<td style=\"width: 20%; height: 48px;\">Post-IVL<br \/>\n(N=233)<\/td>\n<td style=\"width: 20%; height: 48px;\">Post Stent<br \/>\n(N=410)<\/td>\n<td style=\"width: 20%; height: 48px;\">Final<br \/>\n(N=420)<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 20%; height: 24px;\">Any serious angiographic complications<\/td>\n<td style=\"width: 20%; height: 24px;\">2.6%<\/td>\n<td style=\"width: 20%; height: 24px;\">1.2%<\/td>\n<td style=\"width: 20%; height: 24px;\"><strong>0.2%<\/strong><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 20%; height: 24px;\">Severe dissection (Type D to F)<\/td>\n<td style=\"width: 20%; height: 24px;\">2.6%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.4%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 20%; height: 24px;\">Perforation<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.7%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.2%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 20%; height: 24px;\">Abrupt closure<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.5%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 20%; height: 24px;\">Slow flow<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 20%; height: 24px;\">No-reflow<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<td style=\"width: 20%; height: 24px;\">0.0%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h3>DISRUPT CAD Pooled Sex-Specific Analysis, Male Patients<\/h3>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 33.3333%;\">Parameter<\/td>\n<td style=\"width: 33.3333%;\">Post-IVL (N=435)<\/td>\n<td style=\"width: 33.3333%;\">Final (N=484)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Any serious angiographic complications<\/td>\n<td style=\"width: 33.3333%;\">2.3%<\/td>\n<td style=\"width: 33.3333%;\">0.4%<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Severe dissection (Type D to F)<\/td>\n<td style=\"width: 33.3333%;\">1.8%<\/td>\n<td style=\"width: 33.3333%;\">0.2%<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Perforation<\/td>\n<td style=\"width: 33.3333%;\">0%<\/td>\n<td style=\"width: 33.3333%;\">0.2%<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Abrupt closure<\/td>\n<td style=\"width: 33.3333%;\">0%<\/td>\n<td style=\"width: 33.3333%;\">0.2%<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">Slow flow<\/td>\n<td style=\"width: 33.3333%;\">0.5%<\/td>\n<td style=\"width: 33.3333%;\">0%<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 33.3333%;\">No-reflow<\/td>\n<td style=\"width: 33.3333%;\">0%<\/td>\n<td style=\"width: 33.3333%;\">0%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">EMPOWER CAD had 233 lesions, and DISRUPT CAD Pooled Sex-Specific Male Analysis had 435 lesions with available angiography for post-IVL angiographic complication analysis.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_3a0e9fd9dbfbbbfd3f59caa545b1a797\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Quality of Life at 30 Days<\/h2>\n<p>Shockwave IVL was shown to significantly improve quality of life at 30 days in a challenging, complex female patient cohort\u200b.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-13641 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/03\/QoL_30_Days_EMPOWER-CAD.png\" alt=\"\" width=\"1024\" height=\"402\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/03\/QoL_30_Days_EMPOWER-CAD.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/03\/QoL_30_Days_EMPOWER-CAD-300x118.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/03\/QoL_30_Days_EMPOWER-CAD-768x302.png 768w\" data-sizes=\"(max-width: 1024px) 100vw, 1024px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1024px; --smush-placeholder-aspect-ratio: 1024\/402;\" \/><\/p>\n<p>\u00a0<\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_4f0daf48e34c5c1628830f1e8a153ba5\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"takeaways\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2 data-ccp-props=\"{\"335551550\":1,\"335551620\":1,\"335559683\":0,\"335559685\":0,\"335559731\":0,\"335559737\":0,\"335562764\":2,\"335562765\":1,\"335562766\":4,\"335562767\":10,\"335562768\":4,\"335562769\":0}\"><span data-usefontface=\"true\" data-contrast=\"none\">Shockwave IVL-first* Strategy Successful in a Female Population<\/span>\u200b\u200b<\/h2>\n<p>In a high-risk patient population that has typically seen underwhelming results with other calcium modification modalities, EMPOWER CAD demonstrates first-in-class safety and effectiveness utilizing an IVL-first* strategy.<sup>5<\/sup><\/p>\n<p data-ccp-props=\"{\"335551550\":1,\"335551620\":1,\"335559683\":0,\"335559685\":0,\"335559731\":0,\"335559737\":0,\"335562764\":2,\"335562765\":1,\"335562766\":4,\"335562767\":10,\"335562768\":4,\"335562769\":0}\">\u200b<\/p>\n<p>\u00a0<\/p>\n\t<\/div>\n\t<\/section>\n\n\n<!-- BLOCK CONTENT -->\n<section id=\"block_fb3d090ebc30dce98719422ae04ce8f1\"  class=\"block block--section \">\n\t<div class=\"container\">\n\t\t\n\n<section id=\"block_5864b805f55b02800a387dad2bfaf465\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_5864b805f55b02800a387dad2bfaf465-card-0\" role=\"listitem\" aria-labelledby=\"block_5864b805f55b02800a387dad2bfaf465-card-0-number\" aria-describedby=\"block_5864b805f55b02800a387dad2bfaf465-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_5864b805f55b02800a387dad2bfaf465-card-0-number\">90.6<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_5864b805f55b02800a387dad2bfaf465-card-0-description\">\n\t\t\t\t\t\tLesions in which Shockwave IVL-first* approach was used\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-0\" role=\"listitem\" aria-labelledby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-0-number\" aria-describedby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-0-number\">87.4<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-0-description\">\n\t\t\t\t\t\tProcedural success\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-1\" role=\"listitem\" aria-labelledby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-1-number\" aria-describedby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-1-number\">98.5<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-1-description\">\n\t\t\t\t\t\tStent delivery<sup>7<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-2\" role=\"listitem\" aria-labelledby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-2-number\" aria-describedby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-2-number\">98.5<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-2-description\">\n\t\t\t\t\t\tWith less or equal to 30% residual stenosis\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-3\" role=\"listitem\" aria-labelledby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-3-number\" aria-describedby=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-3-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-3-number\">2.6<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_a7b9e9728f6ecfbb3243c1481bf16bd7-card-3-description\">\n\t\t\t\t\t\tPost IVL serious angiographic complication rate\r\n\r\n\r\n\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_4f0daf48e34c5c1628830f1e8a153ba5\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"videos\" class=\"block block--content-3-or-4-up text_colors shockwave\" aria-labelledby=\"section-heading-videos\">\n\t<div class=\"container\">\n\n\t\t<!-- Header -->\n\t\t\t\t\t<header class=\"heading-row\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"section-heading-videos\" class=\"optional-heading\">\n\t\t\t\t\t\tEMPOWER Video Highlights\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/header>\n\t\t\n\t\t<!-- Cards Section -->\n\t\t<ul class=\"cards three-cards\" role=\"list\">\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/04\/Complex-PCI-in-Women-ft.-Dr.-Suzanne-Baron-thumbnail.jpg\"\n\t\t\t\t\t\t\t\talt=\"Image for Complex PCI in Women\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Complex PCI in Women<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Dr. Suzanne Baron outlines the growing need to EMPOWER, highlighting the studies that detail the discrepancies in PCI between females and males.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/de\/education\/empower-cad-video-highlights\/#baron\" target=\"_blank\" aria-label=\"Read more about Complex PCI in Women\" >Watch Video<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/04\/EMPOWER-CAD-Case-Highlight-ft.-Dr.-Kevin-Croce-thumbnail.jpg\"\n\t\t\t\t\t\t\t\talt=\"Image for IVL is Safe and Effective in Men and Women\u00b2\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">IVL is Safe and Effective in Men and Women\u00b2<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Nodular calcium poses a big clinical problem that is predominantly represented in female patients. Calcified nodules have worse long-term outcomes than any other presentation of calcium.<sup>3<\/sup> Dr. Kevin Croce\u2019s patient presented with a challenging tortuous nodular calcified lesion in the right coronary artery. A Shockwave C2 + IVL catheter was used to successfully treat the nodular calcium safely and effectively.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/de\/education\/empower-cad-video-highlights\/#croce\" target=\"_blank\" aria-label=\"Read more about IVL is Safe and Effective in Men and Women\u00b2\" >Watch the Case Review<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/04\/Complex-PCI-in-Women-ft.-Dr.-Nieves-Gonzalo-thumbnail.jpg\"\n\t\t\t\t\t\t\t\talt=\"Image for Consistent Results Regardless of Complex Anatomy\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Consistent Results Regardless of Complex Anatomy<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">The main challenges for calcific lesion treatment in women are related with vessel size and tortuosity.<sup>4<\/sup> Dr. Nieves Gonzalo\u2019s patient presented with both challenges in the left anterior descending artery and the circumflex artery. After visualizing how severe the calcium was in both arteries, a 2.5 Shockwave C2+ catheter was used to modify the calcium. IVL has proven to be impactful and safe for the treatment of calcific coronary disease in females. <\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/de\/education\/empower-cad-video-highlights\/#gonzalo\" target=\"_blank\" aria-label=\"Read more about Consistent Results Regardless of Complex Anatomy\" >Watch the Case Review<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_226f9b6603e46d94b68b340475078b04\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">Drs. Baron and Croce are paid consultants of Shockwave Medical.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section id=\"block_94987804a9a126675e912b9fa0a263ec\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors \">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">More Coronary Clinical Studies<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/?technology_terms%5B%5D=coronary-ivl&sort_order=date_desc&pageNumber=1\" target=\"_self\" aria-label=\"See All Coronary Studies - link to page\" >See All Coronary Studies<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/?technology_terms%5B%5D=coronary-ivl&sort_order=date_desc&pageNumber=1\" target=\"_self\" aria-label=\"See All Coronary Studies - link to page\" >See All Coronary Studies<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-8042\" aria-describedby=\"post-category-8042 post-excerpt-8042\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-8042\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/cad-pooled\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT CAD Pooled\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-8042\">\n\t\t\t\t\t\tThe\u202flargest systematic assessment of Shockwave coronary Intravascular Lithotripsy (IVL) to date based on individual patient data from DISRUPT CAD I\u2013IV.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-8042\">\n\t\t\t\t\t\tCoronary IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-8004\" aria-describedby=\"post-category-8004 post-excerpt-8004\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-8004\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/cad-iii\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT CAD III\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-8004\">\n\t\t\t\t\t\tLargest and most rigorous Shockwave study showcasing the safety, effectiveness and ease of use of Shockwave coronary IVL\u202f.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-8004\">\n\t\t\t\t\t\tCoronary IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-8038\" aria-describedby=\"post-category-8038 post-excerpt-8038\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-8038\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/de\/clinical-evidence\/cad-iv\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT CAD IV\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-8038\">\n\t\t\t\t\t\tShockwave coronary study demonstrating the safety and effectiveness of Shockwave IVL within a Japanese patient population. \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-8038\">\n\t\t\t\t\t\tCoronary IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>\n\n\n\n<section id=\"block_c3369d3b3422cbd4981a0c97cb492e52\" class=\"block block--resource-list text_colors \">\n\t<div class=\"block__container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"block_c3369d3b3422cbd4981a0c97cb492e52-heading\" class=\"heading\">\n\t\t\t\t\tAdditional Resources\t\t\t\t<\/h3>\n\t\t\t\n\t\t\t\t\t\t\t<ul class=\"resource-list--links-container\" role=\"list\" aria-label=\"Resource links\" style=\"--column-count: 3;\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line\" href=\"https:\/\/www.jscai.org\/article\/S2772-9303(24)01733-2\/fulltext\" target=\"_blank\" aria-label=\"JSCAI: EMPOWER Study Design Publication - opens in a new tab\" rel=\"noopener\"><span class=\"text-content\">JSCAI: EMPOWER Study Design Publication<\/span><i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line\" href=\"https:\/\/www.youtube.com\/watch?v=xTgagSRtOo0\" target=\"_blank\" aria-label=\"SCAI: Sex-Specific Considerations in Revascularization - opens in a new tab\" rel=\"noopener\"><span class=\"text-content\">SCAI: Sex-Specific Considerations in Revascularization<\/span><i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line\" href=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/03\/EMPOWER-One-Pager.pdf\" target=\"_blank\" aria-label=\"Download the One Page Summary - download asset\" download><span class=\"text-content\">Download the One Page Summary<\/span><i aria-hidden=\"true\" class=\"fa-arrow-down-to-bracket fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line\" href=\"https:\/\/www.jscai.org\/article\/S2772-9303(25)01637-0\/fulltext\" target=\"_blank\" aria-label=\"Read the Publication - opens in a new tab\" rel=\"noopener\"><span class=\"text-content\">Read the Publication<\/span><i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_7856d9e8ee24e1b79ceffdeca1b09533\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\"><span class=\"legal_copy\">*Shockwave IVL-first algorithm: the utilization of a non-compliant balloon first, and subsequently if the lesion was found to need additional therapy, and Shockwave IVL could pass, it was the front-line calcium modification tool used. Additional tools were used only if needed after IVL at the operator\u2019s discretion.\u200b<br \/>\n**449 target lesions treated is the number of site reported lesions. 430 is the number of core lab reported lesions for EMPOWER CAD.<br \/>\n<\/span><\/span><\/p>\n<p>\u00a0<\/p>\n<p><span class=\"legal_copy\">1. McEntegart, Margaret et al. Treating Women With Calcified Coronary Arteries Using Intravascular Lithotripsy: Primary Results of the EMPOWER CAD Study, Journal of the Society for Cardiovascular Angiography & Interventions, 2026, 104191<br \/>\n2. Lansky, Alexandra et al. SCAI Expert Consensus Statement on Sex-Specific Considerations in Myocardial Revascularization. Journal of the Society for Cardiovascular Angiography & Interventions. 2022; 100016<br \/>\n3. Shaw, Leslee et al., Sex differences in calcified plaque and long-term cardiovascular mortality: observations from the CAC Consortium, European Heart Journal. 2018; 101093<br \/>\n4. Hussain, Yasin et al. Sex-Specific Outcomes After Coronary Intravascular Lithotripsy: A Patient-Level Analysis of the Disrupt CAD Studies., Journal of the Society for Cardiovascular Angiography & Interventions, 2002; 100011<br \/>\n5. Ford, Thomas et al., Sex differences in procedural and clinical outcomes following rotational atherectomy, Catheterization & Cardiovascular Interventions, 2019; 101002<br \/>\n<\/span><span class=\"legal_copy\">6. Hill, J., et al., Intravascular Lithotripsy for Treatment of Severely Calcified Coronary Artery Disease, Journal of the American College of Cardiology, 2020; 101016<br \/>\n<\/span><span class=\"legal_copy\">7. M. McEntegart et al. Women with Calcified Coronary Arteries Treated With Intravascular Lithotripsy. Presented at EuroPCR 2025. May 20, 2025<br \/>\n<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_d0d0eb11d54acd2665c28c0f38936b2b\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>The first prospective, female-only study of coronary interventions in complex calcific disease, in collaboration with female leaders. <\/p>\n","protected":false},"featured_media":3996,"template":"","format":[],"meta":{"_acf_changed":true,"content-type":""},"disease-state":[161],"product-tag":[257,253],"specialty":[297,330,334,338,346],"technology":[318],"class_list":["post-8049","clinical-evidence","type-clinical-evidence","status-publish","has-post-thumbnail","hentry","disease-state-coronary-artery-disease-de","product-tag-shockwave-c2-de-2","product-tag-shockwave-c2-de","specialty-fellows-residents-de","specialty-interventional-cardiologists-de","specialty-interventional-radiologists-de","specialty-nurses-technologists-de","specialty-vascular-surgeons-de","technology-coronary-ivl-de"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/clinical-evidence\/8049","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/clinical-evidence"}],"about":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/types\/clinical-evidence"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media\/3996"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media?parent=8049"}],"wp:term":[{"taxonomy":"disease-state","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/disease-state?post=8049"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/format?post=8049"},{"taxonomy":"product-tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/product-tag?post=8049"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/specialty?post=8049"},{"taxonomy":"technology","embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/technology?post=8049"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}