{"id":7100,"date":"2024-11-06T10:51:18","date_gmt":"2024-11-06T16:51:18","guid":{"rendered":"https:\/\/shockwavemedical.com\/coronary-sinus-reduction-refractory-angina\/"},"modified":"2025-09-18T14:53:32","modified_gmt":"2025-09-18T19:53:32","slug":"coronary-sinus-reduction","status":"publish","type":"page","link":"https:\/\/shockwavemedical.com\/de\/disease-states\/coronary-sinus-reduction\/","title":{"rendered":"Coronary Sinus Reduction for Refractory Angina\u00a0\u00a0"},"content":{"rendered":"\n\n\n<section id=\"block_374fb82a3fdcc8f021db9df6780ba33e\" class=\"block block--primary-header u-darkMode u-bgColor_primary\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2023\/04\/Reducer-Background-2.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">Verengung des Koronarvenensinus bei refrakt\u00e4rer Angina pectoris<\/h1>\n\t\t\t<h3 class=\"sub-heading\">Schmerzlinderung. Hoffnung wiederherstellen. Millionen von Patienten mit koronarer Herzkrankheit (KHK) leiden trotz optimaler medikament\u00f6ser Therapie unter refrakt\u00e4rer Angina pectoris. Der Shockwave Reducer ist darauf ausgelegt, die Symptome der refrakt\u00e4ren Angina durch eine permanente, kontrollierte Verengung des Koronarvenensinus zu verbessern.*<\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\t\t\t<div class=\"links\">\n\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line optional-button on-dark\" href=\"https:\/\/shockwavemedical.com\/de\/reducer-overview-moa\/\" target=\"_self\" aria-label=\"\u00dcberblick \u00fcber den Shockwave Reducer und den Wirkmechanismus - link to page\" >\u00dcberblick \u00fcber den Shockwave Reducer und den Wirkmechanismus<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\n<a data-atom=\"button\" class=\"btn--line optional-button on-dark\" href=\"https:\/\/shockwavemedical.com\/de\/products\/reducer\/\" target=\"_self\" aria-label=\"Shockwave Reducer - link to page\" >Shockwave Reducer<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t<\/div>\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2023\/04\/Shockwave_Reducer_Hero_Flipped.png\" alt=\"Digital rendering of reducer device\" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t\t\t<div class=\"mobile-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2023\/04\/Shockwave_Reducer_Hero_Flipped.png\" alt=\"Digital rendering of reducer device\" role=\"img\" aria-label=\"Foreground image for mobile\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_e5dd1831367689fd208a83b130a5b064\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_b59b2331fa90c2333311d0c6c9a11ab7\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2><img decoding=\"async\" class=\"size-medium wp-image-10499 alignnone lazyload\" style=\"--smush-placeholder-width: 300px; --smush-placeholder-aspect-ratio: 300\/79;padding: 0;\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Logo-300x79.png\" alt=\"\" width=\"300\" height=\"79\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Logo-300x79.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Logo-1024x270.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Logo-768x202.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Logo-1536x405.png 1536w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Logo.png 2000w\" data-sizes=\"(max-width: 300px) 100vw, 300px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" \/><\/h2>\n<h2>Verbesserung der Behandlungsergebnisse: Perkutane Behandlungsoption f\u00fcr refrakt\u00e4re Angina pectoris<\/h2>\n<p>Angina pectoris ist in der Regel ein Symptom der myokardialen Isch\u00e4mie (Mangel an Blutfluss zum Herzmuskel) und \u00e4u\u00dfert sich oftmals als Druck- oder Engegef\u00fchl in der Brust und\/oder Schmerzen in den Schultern, Armen, im Nacken, Kiefer oder R\u00fccken. Viele Patienten mit Angina pectoris leiden unter Symptomen, die schwerwiegend, langanhaltend und durch herk\u00f6mmliche medizinische Therapien nicht kontrollierbar sind. Diese schwerwiegende Erkrankung wird als refrakt\u00e4re Angina pectoris bezeichnet.<\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"4\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Schmerzen der Angina pectoris sind oft ein Symptom der KHK, wenn Plaqueansammlungen in den Arterien auftreten, was das Herz dazu zwingt, st\u00e4rker zu arbeiten<\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"4\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Viele Patienten k\u00f6nnen Linderung ihrer Schmerzen der Angina pectoris durch Revaskularisation mittels koronarer Intervention oder Bypassoperation erfahren. Dennoch leiden 25\u201340 % selbst nach erfolgreicher Revaskularisation weiterhin unter Angina.<sup>1, 2 <\/sup><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"4\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Angina bei nicht obstruktiven koronaren Arterien (ANOCA) wird zunehmend anerkannt und k\u00f6nnte bis zu einem Drittel der Patienten betreffen, die sich einer invasiven Koronarangiographie aufgrund eines Verdachts auf KHK unterziehen.<sup>3, 4<\/sup> Diese Patienten haben keine Plaqueansammlungen als Ursache f\u00fcr ihre Angina. Derzeit stehen nur begrenzte Behandlungsm\u00f6glichkeiten zur Verf\u00fcgung.<\/li>\n<\/ul>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_ff7c4641cbcf659df1c417156f5d9189\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_cfe775d7ba714b7283a853bcb3ba36b9\" class=\"block block--youtube-video-with-text-overlay text_colors \">\n\t<div class=\"block__container\">\n\t\t<div class=\"thumbnail\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/07\/Shockwave-Reducer_Story-of-Flow_thumbnail.jpg\" alt=\"Shockwave Reducer: A Story of Flow\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<div class=\"play-button-container\">\n\t\t\t\t<button type=\"button\" aria-label=\"Play video\" class=\"play-button btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-solid fa-play\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t<!-- Heading, description, and button -->\n\t\t<div class=\"heading-description-button\">\n\t\t\t\t\t\t\t<h2 class=\"heading\">\n\t\t\t\t\tShockwave Reducer: Eine Geschichte des Blutflusses\t\t\t\t<\/h2>\n\t\t\t\n\t\t\t\t\t\t\t<p class=\"description\">\n\t\t\t\t\tIn dieser kurzen Animation zeigen wir die Blutzirkulation in den Herzkranzgef\u00e4\u00dfen. Die Animation zeigt, wie der Blutfluss in einem gesunden Herz verl\u00e4uft und welche Ver\u00e4nderungen bei einer obstruktiven koronaren Herzkrankheit auftreten. Au\u00dferdem wird dargestellt wie der hypothetische Wirkmechanismus (MOA) des Shockwave Reducers hilft, den Widerstand des ven\u00f6sen Abflusses zu erh\u00f6hen und so einen R\u00fcckstau erzeugt, der den Blutfluss in das Subendokard wiederherstellt. Dieses Video wurde in Zusammenarbeit mit OPTIMA erstellt.\t\t\t\t<\/p>\n\t\t\t\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div class=\"video-modal\" role=\"dialog\" aria-modal=\"true\" aria-labelledby=\"modal-title-block_cfe775d7ba714b7283a853bcb3ba36b9\" style=\"display: none;\">\n\t\t\t\t<button type=\"button\" aria-label=\"Close modal\" class=\"modal-close btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-xmark\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t\t<div class=\"modal-content\">\n\t\t\t\t\t<h2 id=\"modal-title-block_cfe775d7ba714b7283a853bcb3ba36b9\" class=\"sr-only\">Video Player<\/h2>\n\t\t\t\t\t<lite-youtube videoid=\"l4rlJf22BDw\" style=\"width: 100%; height: 100%;\" title=\"Shockwave Reducer: A Story of Flow\"><\/lite-youtube>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_ff7c4641cbcf659df1c417156f5d9189\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"study-results\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Wachsende klinische Evidenz: Studienergebnisse<\/h2>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_5370c86a544ca6f7fbb913a9fb865dd0\" class=\"block block--accordion text_colors \">\n\n\t\t<div class=\"accordion__wrapper container\">\n\t\t\n\t\t\t\t\t\t<div class=\"accordion__top u-animation\">\n\t\t\t\t<h2 id=\"accordion-title-block_5370c86a544ca6f7fbb913a9fb865dd0\" class=\"sr-only\">Accordion Section<\/h2>\n\t\t\t\t\n\t\t\t\t\t<div class=\"accordion\" data-layout=\"default_item\">\n\t\t\t\t\t\t<h3 class=\"accordion__trigger toggle__wrapper\">\n\t\t\t\t\t\t<button class=\" btn\" aria-expanded=\"false\" aria-controls=\"accordion-item-block_5370c86a544ca6f7fbb913a9fb865dd0-0\">\n\t\t\t\t\t\t\tREDUCER-I prospektive, multizentrische, Postmarket Studie\t\t\t\t\t\t\t<div class=\"accordion-toggle\">\n\t\t\t\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-chevron-down shockwave\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-plus jj\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/button>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t<div id=\"accordion-item-block_5370c86a544ca6f7fbb913a9fb865dd0-0\" class=\"accordion__content\">\n\t\t\t\t\t\t\t<div class=\"grid grid--column grid-md--row-reverse\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"grid__col u-wysiwyg wysiwyg_styles\">\n\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">REDUCER-I 12-month results demonstrated the safety and efficacy of the Reducer in improving angina severity and quality of life in patients suffering from refractory angina.<\/span><sup><span data-contrast=\"auto\">5<\/span><\/sup><span data-contrast=\"auto\"> Additionally, the outcomes showed a reduction in emergency department visits after Reducer implantation as well as clinically significant increase in the 6 Minute Walk Test distance. The results of the 400 patients enrolled at 25 centres and followed up to three years further augmented the findings from the initial COSIRA trial.<\/span><sup><span data-contrast=\"auto\">6 <\/span><\/sup><span data-ccp-props=\"{\"335559685\":0}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"9\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">71% of patients improved one or more CCS angina classes at 12 months\u2020<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"9\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">26% of patients improved two or more CSS angina classes at 12 months<\/span><span data-ccp-props=\"{}\">\u2020<\/span><\/li>\n<\/ul>\n<p><a href=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Reducer-I-Observational-Study-12-month-Results.pdf\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"auto\">Download 12-month results<\/span><\/a><\/p>\n<p>Die REDUCER-I-Subanalyse von Patienten mit nicht-obstruktiver KHK*, die einen Reducer erhielten, zeigte nach 12 Monaten eine statistisch signifikante Verbesserung der Lebensqualit\u00e4t (QoL) und eine Verbesserung der CCS-Klasse.<\/p>\n<p><em>Die nicht-obstruktive KHK ist definiert als Stenose von weniger als 70 %in allen gro\u00dfen epikardialen Koronararterien, nach visueller Sch\u00e4tzung.<\/em><\/p>\n<ul>\n<li>Sowohl bei der obstruktiven KHK (p<0,0001) als auch bei der nicht-obstruktiven KHK (p<0,0002) waren nach 12 Monaten signifikante Verbesserungen im mittleren SAQ Summary Score zu verzeichnen<\/li>\n<li>Sowohl die obstruktive KHK- als auch die nicht-obstruktive KHK-Patientengruppen zeigten nach 12 Monaten eine verbesserte CCS-Klasse ohne, dass zwischen den Gruppen signifikante Unterschiede (p=0,1178) auftraten<\/li>\n<\/ul>\n<p><a href=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/07\/REDUCER-I-Non-Obstructive-Disease-Data.pdf\" target=\"_blank\" rel=\"noopener\">Subanalysedaten herunterladen<\/a><\/p>\n<p><span class=\"legal_copy\"><sup>\u2020<\/sup>Gepaarte Analyse f\u00fcr Patienten mit Baseline- und 12-Monats- CCS-Klassifikation. <\/span><\/p>\n<p><span class=\"legal_copy\">*KHK = koronare Herzkrankheit<\/span><\/p>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\n\t\t\t\t\t<div class=\"accordion\" data-layout=\"default_item\">\n\t\t\t\t\t\t<h3 class=\"accordion__trigger toggle__wrapper\">\n\t\t\t\t\t\t<button class=\" btn\" aria-expanded=\"false\" aria-controls=\"accordion-item-block_5370c86a544ca6f7fbb913a9fb865dd0-1\">\n\t\t\t\t\t\t\tORBITA-COSMIC randomisierte, Placebo-kontrollierte Studie\t\t\t\t\t\t\t<div class=\"accordion-toggle\">\n\t\t\t\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-chevron-down shockwave\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-plus jj\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/button>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t<div id=\"accordion-item-block_5370c86a544ca6f7fbb913a9fb865dd0-1\" class=\"accordion__content\">\n\t\t\t\t\t\t\t<div class=\"grid grid--column grid-md--row-reverse\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"grid__col u-wysiwyg wysiwyg_styles\">\n\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">Results of the independent ORBITA-COSMIC trial show Shockwave Reducer lessens angina frequency and improves heart disease related quality of life while improving subendocardial perfusion.<\/span><sup><span data-contrast=\"auto\">7 <\/span><\/sup><span data-contrast=\"auto\">5<\/span><span data-contrast=\"auto\">1 patients were randomized at six centres in the UK. Shockwave Reducer decreased the number of daily angina episodes compared to placebo at six months.<\/span><span data-ccp-props=\"{\"201341983\":0,\"335559740\":259}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"6\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">The results showed evidence of benefit on angina frequency reported using the smartphone ORBITA-app in the coronary sinus reducer (CSR) group compared to the placebo group<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"6\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Heart disease-related quality of life measured by MacNew Heart Disease Health-Related Quality of Life scores improved in the CSR group compared with the placebo group<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"6\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">While the primary imaging endpoint showed no improvement in transmural myocardial perfusion, it did show improvement in subendocardial perfusion, supporting the theorized mechanism of action of the Shockwave Reducer<\/li>\n<\/ul>\n<p><a href=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-ORBITA-COSMIC-Trial-Results-Brochure.pdf\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"auto\">Download results<\/span><\/a><\/p>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\n\t\t\t\t\t<div class=\"accordion\" data-layout=\"default_item\">\n\t\t\t\t\t\t<h3 class=\"accordion__trigger toggle__wrapper\">\n\t\t\t\t\t\t<button class=\" btn\" aria-expanded=\"false\" aria-controls=\"accordion-item-block_5370c86a544ca6f7fbb913a9fb865dd0-2\">\n\t\t\t\t\t\t\tCOSIRA prospektive, randomisierte, Sham-kontrollierte Studie\t\t\t\t\t\t\t<div class=\"accordion-toggle\">\n\t\t\t\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-chevron-down shockwave\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-plus jj\" aria-hidden=\"true\"><\/i>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/button>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\t\t<div id=\"accordion-item-block_5370c86a544ca6f7fbb913a9fb865dd0-2\" class=\"accordion__content\">\n\t\t\t\t\t\t\t<div class=\"grid grid--column grid-md--row-reverse\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"grid__col u-wysiwyg wysiwyg_styles\">\n\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">Beginning in 2010, the Reducer team and clinicians worldwide began studying the safety and effectiveness of the Shockwave Reducer device. 104 patients with Canadian Cardiovascular Society (CCS) class III or IV angina and myocardial ischemia who were not candidates for revascularization were enrolled. One randomized group received the device (treatment group) while another received a sham procedure (control group). COSIRA**\u00a0demonstrated patients receiving the Shockwave Reducer device achieved a statistically significant improvement in angina symptoms and quality of life compared to patients in a sham control group.<\/span><sup><span data-contrast=\"auto\">6<\/span><\/sup><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"7\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">71% of patients improved 1 or more CCS angina classes at 6 months<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"7\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">35% of patients improved 2 or more CCS angina classes at 6 months<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"7\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Quality of life improved 17.6 points for patients who received the implant, vs. 7.6 points for patients in the control group<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1402556\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"auto\">Download results<\/span><\/a><\/p>\n<p><span data-contrast=\"auto\">**COSIRA = COronary SInus Reducer for treatment of Refractory Angina <\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\n\t\t\t<\/div>\n\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_ff7c4641cbcf659df1c417156f5d9189\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_8e0d3a6426597587896761a1c7954f40\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Erweiterung klinischer Daten: COSIRA II Studie<\/h2>\n<p>Aktuell einschlie\u00dfend: COSIRA** II ist die aktuell laufende klinische Studie, die darauf abzielt, weitere Evidenz f\u00fcr die Sicherheit und Wirksamkeit des Shockwave Reducers zu sammeln. Die Studie wird in den USA als eine multizentrische, randomisierte, doppelblinde, Sham-kontrollierte Studie durchgef\u00fchrt. ClinicalTrials.gov Identifier: NCT05102019.<\/p>\n<p>**COSIRA = COronary SInus Reducer zur Behandlung der refrakt\u00e4ren Angina<\/p>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_431ba75b9e3232cf5a9053366c32534c\" class=\"block block--content-3-or-4-up text_colors \" aria-labelledby=\"section-heading-block_431ba75b9e3232cf5a9053366c32534c\">\n\t<div class=\"container\">\n\n\t\t<!-- Header -->\n\t\t\n\t\t<!-- Cards Section -->\n\t\t<ul class=\"cards three-cards\" role=\"list\">\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Coronary-Sinus-Reducer-thumbnail.jpg\"\n\t\t\t\t\t\t\t\talt=\"youtube thumbnail screenshot of presenter speaking at TCT\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">COSIRA II Symposium: The Coronary Sinus Reducer <\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/de\/education\/shockwave-cosira-ii-symposium-the-coronary-sinus-reducer\/\" target=\"_self\" aria-label=\"Read more about COSIRA II Symposium: The Coronary Sinus Reducer \">Video ansehen<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/reducer-angina-thumbnal.jpg\"\n\t\t\t\t\t\t\t\talt=\"youtube thumbnail screenshot of presenter speaking at TCT\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">COSIRA II Symposium: Angina: The Scope of the Challenge <\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/de\/education\/cosira-ii-symposium-angina-the-scope-of-the-challenge\/\" target=\"_self\" aria-label=\"Read more about COSIRA II Symposium: Angina: The Scope of the Challenge \">Video ansehen<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/reducer-future.jpg\"\n\t\t\t\t\t\t\t\talt=\"youtube thumbnail screenshot of presenter speaking at TCT\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">COSIRA II Symposium: The Future of Clinical Data for the Reducer <\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/de\/education\/cosira-ii-symposium-the-future-of-clinical-data-for-the-reducer\/\" target=\"_self\" aria-label=\"Read more about COSIRA II Symposium: The Future of Clinical Data for the Reducer \">Video ansehen<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_5ee840372146b7c52b25932716af7a4a\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p>Die beteiligten \u00c4rzte sind bezahlte Berater f\u00fcr Shockwave Medical.<\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_ff7c4641cbcf659df1c417156f5d9189\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"resources\" class=\"block block--resource-list text_colors \">\n\t<div class=\"block__container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"resources-heading\" class=\"heading\">\n\t\t\t\t\tResources\t\t\t\t<\/h3>\n\t\t\t\n\t\t\t\t\t\t\t<ul class=\"resource-list--links-container\" role=\"list\" aria-label=\"Resource links\" style=\"--column-count: 3;\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line\" href=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Spec-Sheet.pdf\" target=\"_blank\" aria-label=\"Shockwave Reducer Product Spec Sheet - download asset\" download><span class=\"text-content\">Shockwave Reducer Product Spec Sheet<\/span><i aria-hidden=\"true\" class=\"fa-arrow-down-to-bracket fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line\" href=\"https:\/\/ifu.sw-reducer.com\/\" target=\"_blank\" aria-label=\"Shockwave Reducer Instructions for Use - opens in a new tab\" rel=\"noopener\"><span class=\"text-content\">Shockwave Reducer Instructions for Use<\/span><i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line\" href=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave-Reducer-Physician-Brochure.pdf\" target=\"_blank\" aria-label=\"Shockwave Reducer Brochure - download asset\" download><span class=\"text-content\">Shockwave Reducer Brochure<\/span><i aria-hidden=\"true\" class=\"fa-arrow-down-to-bracket fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_ff7c4641cbcf659df1c417156f5d9189\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_7ab488ec8f3c6bbcf244c7d2a438b940\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<hr \/>\n<p><span class=\"legal_copy\">*Shockwave Reducer is commercially available in select European countries and has been implanted in over 3,500 patients. It is currently under clinical investigation in the U.S. <\/span><\/p>\n<p><span class=\"legal_copy\"><strong>Caution:<\/strong> In the United States, Shockwave Reducer is an investigational device, limited by United States law to investigational use. The Reducer is subject of Investigational testing and is being studied in the COSIRA-II trial in Canada. <\/span><\/p>\n<p><span class=\"legal_copy\">Shockwave Reducer is commercially available in certain countries outside the U.S. and Canada. Please contact your local representative for specific country availability. Prior to use, please reference the Instructions for Use for more information on warnings, precautions and adverse events: <a href=\"https:\/\/ifu.sw-reducer.com\/\" target=\"_blank\" rel=\"noopener\">ifu.sw-reducer.com<\/a><\/span><\/p>\n<p><span class=\"legal_copy\">1: Abdallah, M. J Am Coll Cardiol 2017;69:2039-50.<br \/>\n2: Stone, G. 2-year results from the ABSORB IV randomized trial. TCT 2019.<br \/>\n3: Patel, M. N Engl J Med 2010; 362:886-895.<br \/>\n4: Samuels, B. J Am Coll Cardiol 2023; 82:1245-1263.<br \/>\n5: Verheye, S. Results from the REDUCER-I Study. ESC 2024.<br \/>\n6: Verheye S, Jolicoeur EM, Behan MW, et al. Efficacy of a device to narrow the coronary sinus in refractory angina. N Engl J Med 2015; 372: 519-527.<br \/>\n7: Foley et al. The Lancet. 2024 Apr 8; https:\/\/doi.org\/10.1016\/S0140-6736(24)00256-3.<br \/>\n<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_ff7c4641cbcf659df1c417156f5d9189\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Shockwave Reducer is designed to treat the symptoms of refractory angina through a permanent, controlled narrowing of the coronary sinus.<\/p>\n","protected":false},"author":15,"featured_media":4046,"parent":9781,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"class_list":["post-7100","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/pages\/7100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/comments?post=7100"}],"version-history":[{"count":0,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/pages\/7100\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/pages\/9781"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media\/4046"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/de\/wp-json\/wp\/v2\/media?parent=7100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}