{"id":13041,"date":"2025-11-03T14:00:00","date_gmt":"2025-11-03T20:00:00","guid":{"rendered":"https:\/\/shockwavemedical.com\/?post_type=clinical-evidence&#038;p=13041"},"modified":"2026-02-23T08:53:08","modified_gmt":"2026-02-23T14:53:08","slug":"disrupt-btk-ii-clti-cohort-analysis","status":"publish","type":"clinical-evidence","link":"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/disrupt-btk-ii-clti-cohort-analysis\/","title":{"rendered":"DISRUPT BTK II CLTI Cohort Analysis"},"content":{"rendered":"\n\n\n<section id=\"block_df70133f870e2b9a0a6d940da5030999\" class=\"block block--primary-header u-darkMode u-bgColor_primary\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Background-Pulses.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">DISRUPT BTK II CLTI Cohort Analysis<\/h1>\n\t\t\t<h3 class=\"sub-heading\">Count on it: New data validates Shockwave Intravascular Lithotripsy\u2019s (IVL) impact on patients with chronic limb threatening ischemia (CLTI) at 12 months. DISRUPT BTK II assessed the continued safety and effectiveness of the Shockwave Peripheral IVL System for the treatment of calcified, stenotic lesions in below-the-knee (BTK) arteries. This sub-analysis focuses on results from the patients with CLTI enrolled in the study.<\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Analysis-Hero-Logo.png\" alt=\"DISRUPT BTK II CLTI Cohort Analysis logo\" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t<\/div>\n<\/section>\n\n\n<section id=\"block_487bc483c591a60c971e45660daee4e9\" class=\"block block--content-3-or-4-up text_colors \" aria-labelledby=\"section-heading-block_487bc483c591a60c971e45660daee4e9\">\n\t<div class=\"container\">\n\n\t\t<!-- Header -->\n\t\t\t\t\t<header class=\"heading-row\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"section-heading-block_487bc483c591a60c971e45660daee4e9\" class=\"optional-heading\">\n\t\t\t\t\t\tCLTI Cohort Key Findings\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/header>\n\t\t\n\t\t<!-- Cards Section -->\n\t\t<ul class=\"cards three-cards\" role=\"list\">\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Wound Healing<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">In a majority of patients with CLTI, IVL plays a critical role in laying the foundation for successful wound healing through safe and effective revascularization.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Limb Salvage<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">12-month outcomes establish IVL\u2019s role in limb salvage and enabling functional recovery in patients with CLTI.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Frontline Strategy<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">The DISRUPT BTK II 12-month data establishes IVL as a frontline calcium modification* for complex BTK lesions, delivering outcomes that redefine the benchmark for success in the treatment of patients with CLTI.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_bdf5fd7f227855c45d36f86ccfbdf347\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">Armstrong E, VIVA 2025. Data on file at Shockwave Medical.<br \/>\n*Frontline strategy: The approach of utilizing IVL as the primary treatment method, implemented without the use of atherectomy. This strategy is backed by the DISRUPT BTK II data based on the percentage of procedures involving pre-dilatation and post-dilatation, as well as the proportion of stenting performed. Our BTK II data indicates a notably low usage of both pre-dilatation and post-stenting in these cases. The majority of patients enrolled had CLTI, thus a majority of the comorbidities are attributed to this population.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"design\" class=\"block block--study-design-patient-chars \" role=\"region\" aria-labelledby=\"design-heading\">\n\t<div class=\"container\">\n\t\t\t\t\t<div class=\"heading-row wysiwyg_styles\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"design-heading\" class=\"heading\">\n\t\t\t\t\t\tDISRUPT BTK II Study Design\t\t\t\t\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"columns wysiwyg_styles\" aria-label=\"Study Design Columns\">\n\t\t\t<div class=\"columns-2-and-3\">\n\t\t\t\t<div class=\"column-2\">\n\t\t\t\t\t<p><b><span data-contrast=\"auto\">Objective<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p>Assess the continued safety and effectiveness of the Shockwave Medical Peripheral IVL System for the treatment of calcified, stenotic lesions in BTK arteries. Products included Shockwave M5+ and Shockwave S4.<\/p>\n<p><strong>Key Inclusion Criteria<\/strong><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"5\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":360,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Rutherford classification (RC) 3-5, RC 3 capped at 20% of enrolled patients<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"5\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":360,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Moderate-severe calcification*<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"5\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":360,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Up to two BTK lesions \u2264 200 mm in length<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-3\">\n\t\t\t\t\t<p><b><span data-contrast=\"auto\">Primary Safety Endpoint<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Major adverse limb events (MALE) or post-operative death (POD) at 30 days<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Primary Effectiveness Endpoint<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Procedural success, defined as <\/span><b><span data-contrast=\"auto\">\u2264 50%<\/span><\/b><span data-contrast=\"auto\"> residual stenosis for all treated target lesions without serious angiographic complications<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Additional analysis to include lesions with <\/span><b><span data-contrast=\"auto\">\u2264 30%<\/span><\/b><span data-contrast=\"auto\"> residual stenosis without angiographic complications<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p>Independent Clinical Events Committee (CEC), Angiographic Core Laboratory, and Duplex Ultrasound Core Laboratory<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"column-1\">\n\t\t\t\t<div class=\"column-1-content\">\n\t\t\t\t\t<div class=\"column-1-content-top\">\n\t\t\t\t\t\tThe DISRUPT BTK II study enrolled the largest cohort of real-world, complex patients* with moderate to severe calcium below the knee\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"column-1-content-bottom\">\n\t\t\t\t\t\tDISRUPT BTK II sets a new benchmark for what\u2019s possible for the challenging lesions. No other technology has been evaluated in such severely calcified BTK lesions to date        \t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-1-arrow\" aria-hidden=\"true\" aria-label=\"Arrow pointing downwards to indicate result\"><i class=\"fa-regular fa-arrow-down\"><\/i><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n\n<section id=\"block_2538691cd1e0f297e704547e03cf4d75\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">*Presence of fluoroscopic evidence of calcification by PARC (Peripheral Academic Research Consortium) definition: 1) on parallel sides of the vessel and 2) extending > 50% the length of the lesion if lesion is \u2265 50 mm in length; or extending for minimum of 20 mm if lesion is < 50 mm in length.\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n<section id=\"demographics\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors has-stat-callout on-dark\">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">Full Cohort By the Numbers<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"on-dark btn--primary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/btk-ii\/\" target=\"_self\" aria-label=\"DISRUPT BTK II - link to page\" >DISRUPT BTK II<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\"on-dark btn--primary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/btk-ii\/\" target=\"_self\" aria-label=\"DISRUPT BTK II - link to page\" >DISRUPT BTK II<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n<section id=\"demographics\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-0\" role=\"listitem\" aria-labelledby=\"demographics-card-0-number\" aria-describedby=\"demographics-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-0-number\">250<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-0-description\">\n\t\t\t\t\t\tPatients\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-1\" role=\"listitem\" aria-labelledby=\"demographics-card-1-number\" aria-describedby=\"demographics-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-1-number\">305<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-1-description\">\n\t\t\t\t\t\tLesions\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-2\" role=\"listitem\" aria-labelledby=\"demographics-card-2-number\" aria-describedby=\"demographics-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-2-number\">38<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-2-description\">\n\t\t\t\t\t\tGlobal sites\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-3\" role=\"listitem\" aria-labelledby=\"demographics-card-3-number\" aria-describedby=\"demographics-card-3-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-3-number\">2<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-3-description\">\n\t\t\t\t\t\tYear follow-up\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t<\/ul>\n<\/section>\n\n\n\n<section id=\"block_4ddbe4d6740b4c13f2638703ef67c431\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><img decoding=\"async\" class=\"aligncenter wp-image-13072 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-RC-Follow-Up-Breakdown-graphic.jpg\" alt=\"Flow chart graphic showing a break-down of the 250 patients enrolled in the DISRUPT BTK II Study by RC 3 versus CLTI\" width=\"2000\" height=\"568\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-RC-Follow-Up-Breakdown-graphic.jpg 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-RC-Follow-Up-Breakdown-graphic-300x85.jpg 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-RC-Follow-Up-Breakdown-graphic-1024x291.jpg 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-RC-Follow-Up-Breakdown-graphic-768x218.jpg 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-RC-Follow-Up-Breakdown-graphic-1536x436.jpg 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/568;\" \/><\/p>\n<p><span class=\"legal_copy\">Armstrong E, VIVA 2025.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_5fecfd9fe700f52a95c96b98d44e89f6\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_5fecfd9fe700f52a95c96b98d44e89f6\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n<section id=\"block_c35005440ff5ee04e58542c65817060d\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors has-stat-callout on-dark\">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">CLTI Cohort By the Numbers<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\n\t\t\t\n<section id=\"block_c35005440ff5ee04e58542c65817060d\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_c35005440ff5ee04e58542c65817060d-card-0\" role=\"listitem\" aria-labelledby=\"block_c35005440ff5ee04e58542c65817060d-card-0-number\" aria-describedby=\"block_c35005440ff5ee04e58542c65817060d-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_c35005440ff5ee04e58542c65817060d-card-0-number\">200<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_c35005440ff5ee04e58542c65817060d-card-0-description\">\n\t\t\t\t\t\tPatients\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_c35005440ff5ee04e58542c65817060d-card-1\" role=\"listitem\" aria-labelledby=\"block_c35005440ff5ee04e58542c65817060d-card-1-number\" aria-describedby=\"block_c35005440ff5ee04e58542c65817060d-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_c35005440ff5ee04e58542c65817060d-card-1-number\">245<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_c35005440ff5ee04e58542c65817060d-card-1-description\">\n\t\t\t\t\t\tLesions\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t<\/ul>\n<\/section>\n\n\n\n<!-- BLOCK CONTENT -->\n<section id=\"block_7aa02b379de4de2fce04afc27310951c\"  class=\"block block--section \">\n\t<div class=\"container\">\n\t\t\n\n<section id=\"block_b11c01fa4ff254dfa4476fb0be81c7fc\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>CLTI Cohort Baseline Demographics<\/h2>\n<h3>Rutherford Category<\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_2f24960eb7261828811cd84676993917\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_2f24960eb7261828811cd84676993917-card-0\" role=\"listitem\" aria-labelledby=\"block_2f24960eb7261828811cd84676993917-card-0-number\" aria-describedby=\"block_2f24960eb7261828811cd84676993917-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_2f24960eb7261828811cd84676993917-card-0-number\">71<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_2f24960eb7261828811cd84676993917-card-0-description\">\n\t\t\t\t\t\tRC 5, minor tissue loss<sup>2<\/sup>*\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_2f24960eb7261828811cd84676993917-card-1\" role=\"listitem\" aria-labelledby=\"block_2f24960eb7261828811cd84676993917-card-1-number\" aria-describedby=\"block_2f24960eb7261828811cd84676993917-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_2f24960eb7261828811cd84676993917-card-1-number\">29<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_2f24960eb7261828811cd84676993917-card-1-description\">\n\t\t\t\t\t\tRC 4, ischemic rest pain<sup>2<\/sup>**\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_34701a0da1c40105060ec1ee8163ec6c\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Medical History<\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_8f33751ca60d0dc60b8001c4d4d963ea\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0\" role=\"listitem\" aria-labelledby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-number\" aria-describedby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-number\">73<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-description\">\n\t\t\t\t\t\tPatients had wounds at baseline<sup>2<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1\" role=\"listitem\" aria-labelledby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-number\" aria-describedby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-number\">18<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-description\">\n\t\t\t\t\t\tHemodialysis-dependent<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2\" role=\"listitem\" aria-labelledby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-number\" aria-describedby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-number\">77<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-description\">\n\t\t\t\t\t\tDiabetes mellitus<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_a71625c93f51544764db453978fd4be5\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Lesions<\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_845b864885b0124f615e2ba8b31c16f4\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-0\" role=\"listitem\" aria-labelledby=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-number\" aria-describedby=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-number\">86<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-description\">\n\t\t\t\t\t\tModerate-severe Ca++<sup>1\u2020<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-1\" role=\"listitem\" aria-labelledby=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-number\" aria-describedby=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-number\">80<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>mm<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-description\">\n\t\t\t\t\t\tMean lesion length<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-2\" role=\"listitem\" aria-labelledby=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-number\" aria-describedby=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-number\">31<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-description\">\n\t\t\t\t\t\tChronic total occlusions (CTOs)<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_95aac30c56f1153fe2508e729a80edc7\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">1: Armstrong E, VIVA 2025.<br \/>\n2: Data on file at Shockwave Medical.<br \/>\n*Per limb 143\/201 | **Per limb 59\/201 | <sup>\u2020<\/sup>PARC Definition<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"results\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_13f709a15e4a19694aab37804e10d759\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Results and conclusion<\/h2>\n<h3>Clinical Procedural Insights in a CLTI Cohort<\/h3>\n<p>In a challenging patient cohort, IVL was shown to be a safe and effective treatment of challenging calcific BTK lesions with minimal need for provisional stenting.<\/p>\n<h4 style=\"text-align: center;\">CONFIRMED SAFETY<\/h4>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">Total Serious Angiographic Complications Post-IVL<sup>2<\/sup><\/td>\n<td style=\"width: 50%;\">Total Serious Angiographic Complications at Final<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">2.3%<\/td>\n<td style=\"width: 50%;\">1.3%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h4 style=\"text-align: center;\">CONFIRMED EFFECTIVENESS<\/h4>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u00a0Average Residual Stenosis Post-IVL<sup>2<\/sup><\/td>\n<td style=\"width: 50%;\">Average Residual Stenosis at Final<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">30.0%<\/td>\n<td style=\"width: 50%;\">25.7%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h4 style=\"text-align: center;\">MINIMAL PROVISIONAL STENTING<\/h4>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">Stent\/Tack Implant Total<sup>2<\/sup><\/td>\n<td style=\"width: 50%;\">Provisional Stent\/Tack Implant<sup>2<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">5.7%<\/td>\n<td style=\"width: 50%;\">2.8%*<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">*Remaining Stent\/Tack implants were part of physicians\u2019 standard algorithm.<br \/>\n1: Armstrong E, VIVA 2025.<br \/>\n2: Data on file at Shockwave Medical.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"clti-video\" class=\"block block--youtube-video-with-text-overlay text_colors \">\n\t<div class=\"block__container\">\n\t\t<div class=\"thumbnail\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/02\/12-month-Cohort-Thumbnail.png\" alt=\"New Data for Patients with Chronic Limb Threatening Ischemia (CLTI) with Dr. Venita Chandra\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1920px; --smush-placeholder-aspect-ratio: 1920\/1080;\" \/>\n\t\t\t\t\t\t<div class=\"play-button-container\">\n\t\t\t\t<button type=\"button\" aria-label=\"Play video\" class=\"play-button btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-solid fa-play\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t<!-- Heading, description, and button -->\n\t\t<div class=\"heading-description-button\">\n\t\t\t\t\t\t\t<h2 class=\"heading\">\n\t\t\t\t\tNew Data for Patients with CLTI\t\t\t\t<\/h2>\n\t\t\t\n\t\t\t\t\t\t\t<p class=\"description\">\n\t\t\t\t\tIn this video, Dr. Venita Chandra shares 12-month outcomes from the DISRUPT BTK II trial, a prospective study evaluating intravascular lithotripsy (IVL) in patients with CLTI\u2014a population that is often excluded from clinical studies due to disease complexity.\t\t\t\t<\/p>\n\t\t\t\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div class=\"video-modal\" role=\"dialog\" aria-modal=\"true\" aria-labelledby=\"modal-title-clti-video\" style=\"display: none;\">\n\t\t\t\t<button type=\"button\" aria-label=\"Close modal\" class=\"modal-close btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-xmark\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t\t<div class=\"modal-content\">\n\t\t\t\t\t<h2 id=\"modal-title-clti-video\" class=\"sr-only\">Video Player<\/h2>\n\t\t\t\t\t<lite-youtube videoid=\"RUaJ7_qq9Xc\" style=\"width: 100%; height: 100%;\" title=\"New Data for Patients with Chronic Limb Threatening Ischemia (CLTI) with Dr. Venita Chandra\"><\/lite-youtube>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_af9ab0c2df8b3b5b140ca5565b030b98\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Freedom from CD-TLR and Patency at 12 Months<\/h3>\n<p>12-month outcomes confirm the durability of IVL through sustained vessel patency and low reintervention rates which lead to limb preservation and ongoing symptom relief.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-13036 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-CD-TLR-Graphic.png\" alt=\"\" width=\"2000\" height=\"715\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-CD-TLR-Graphic.png 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-CD-TLR-Graphic-300x107.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-CD-TLR-Graphic-1024x366.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-CD-TLR-Graphic-768x275.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-CD-TLR-Graphic-1536x549.png 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/715;\" \/><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%; text-align: center;\">Rutherford Category<\/td>\n<td style=\"width: 50%; text-align: center;\">Freedom from CD-TLR at 12 Months<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; text-align: left;\">Full Cohort (n=250)<\/td>\n<td style=\"width: 50%; text-align: center;\">84.5%<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; text-align: left;\">RC 3 (n=50)<\/td>\n<td style=\"width: 50%; text-align: center;\">92.0%<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; text-align: left;\">CLTI Cohort (n=200)<\/td>\n<td style=\"width: 50%; text-align: center;\">82.7%<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; padding-left: 40px; text-align: left;\">RC 4 (n=57)<\/td>\n<td style=\"width: 50%; text-align: center;\">88.0%<sup>2<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; padding-left: 40px; text-align: left;\">RC 5 (n=143)<\/td>\n<td style=\"width: 50%; text-align: center;\">80.3%<sup>2<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 100%; text-align: center;\" colspan=\"2\"><strong>Patency at 12 Months (CLTI)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 100%; text-align: center;\" colspan=\"2\">64.0% (n=80\/125)<sup>1<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">1: Armstrong E, VIVA 2025.<br \/>\n2: Data on file at Shockwave Medical.<br \/>\nClinically driven target revascularization (CD-TLR).<br \/>\nKaplan Meier (KM) is an analysis that uses probability to capture patients lost to follow-up.<br \/>\nFreedom from CD-TLR analysis excluded patients with above the ankle amputation of target limb.<\/span><\/p>\n<p>\u00a0<\/p>\n<h3>Freedom from Major Amputation at 12 Months<\/h3>\n<p>12-month outcomes establish IVL\u2019s role in limb salvage and enabling functional recovery in patients with CLTI.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-13028 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-Major-Amputation-Graphic.png\" alt=\"\" width=\"2000\" height=\"715\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-Major-Amputation-Graphic.png 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-Major-Amputation-Graphic-300x107.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-Major-Amputation-Graphic-1024x366.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-Major-Amputation-Graphic-768x275.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/BTK-II-CLTI-Cohort-Freedom-from-Major-Amputation-Graphic-1536x549.png 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/715;\" \/><\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 144px;\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: center;\">Rutherford Category<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">Freedom from Major Amputation at 12 Months<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: left;\">Full Cohort (n=250)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">94.8%<sup>1<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: left;\">RC 3 (n=50)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">100%<sup>1<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: left;\">CLTI Cohort (n=200)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">93.3%<sup>1<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; padding-left: 40px; text-align: left;\">RC 4 (n=57)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">98.1%<sup>2<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; padding-left: 40px; text-align: left;\">RC 5 (n=143)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">91.2%<sup>2<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">1: Armstrong E, VIVA 2025.<br \/>\n2: Data on file at Shockwave Medical.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_0874b83c0d053df9ca5df33f5df0830c\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Rutherford Classification (RC) Change at 12 Months<\/h3>\n<p>IVL played a critical role in laying the foundation for successful wound healing in patients with CLTI through safe and effective revascularization.<\/p>\n<ul>\n<li>Of the patients remaining at 12 months, <strong>68%<\/strong> were <strong>no longer CLTI<\/strong><sup>1<\/sup><\/li>\n<li><strong>61%<\/strong> of wounds were <strong>healed<\/strong> or <strong>improving<\/strong><sup>1<\/sup>*<\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-13032 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Rutherford-Category-Chart.png\" alt=\"\" width=\"2000\" height=\"643\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Rutherford-Category-Chart.png 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Rutherford-Category-Chart-300x96.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Rutherford-Category-Chart-1024x329.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Rutherford-Category-Chart-768x247.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Rutherford-Category-Chart-1536x494.png 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/643;\" \/><\/p>\n<p><span class=\"legal_copy\">1: Data on file at Shockwave Medical.<br \/>\nAvailable data is 159 limbs out of 200 limbs of patients with CLTI.<br \/>\n*Mean wound follow up time: 157 days.<\/span><\/p>\n<p>\u00a0<\/p>\n<h3>Quality of Life at 12 Months<\/h3>\n<p>As part of revascularization, IVL facilitates sustained symptom improvement for patients with CLTI through 12 months.<\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 12.5%;\" rowspan=\"3\">Breakdown by Attribute<\/td>\n<td style=\"width: 12.5%;\">VascuQoL-6 Attribute<\/td>\n<td style=\"width: 12.5%;\">Activity<\/td>\n<td style=\"width: 12.5%;\">Tired<\/td>\n<td style=\"width: 12.5%;\">Walk<\/td>\n<td style=\"width: 12.5%;\">Concern<\/td>\n<td style=\"width: 12.5%;\">Social<\/td>\n<td style=\"width: 12.5%;\">Pain<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 12.5%;\"><strong>Average Score 12 Months<\/strong><\/td>\n<td style=\"width: 12.5%;\">2.8<\/td>\n<td style=\"width: 12.5%;\">2.6<\/td>\n<td style=\"width: 12.5%;\">3.0<\/td>\n<td style=\"width: 12.5%;\">2.9<\/td>\n<td style=\"width: 12.5%;\">3.1<\/td>\n<td style=\"width: 12.5%;\">2.8<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 12.5%;\"><strong>Average Score Baseline<\/strong><\/td>\n<td style=\"width: 12.5%;\">1.9<\/td>\n<td style=\"width: 12.5%;\">2.0<\/td>\n<td style=\"width: 12.5%;\">2.3<\/td>\n<td style=\"width: 12.5%;\">1.7<\/td>\n<td style=\"width: 12.5%;\">2.3<\/td>\n<td style=\"width: 12.5%;\">1.8<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<p>All categories improved. Total VascuQoL-6 Score (CLTI) at 12 months significantly improved from baseline (P-Value: p<0.001). Total at <em>12 months<\/em> was 17.2 \u00b1 5.0 and total at <em>baseline<\/em> was 11.9 \u00b1 4.0.<sup>1<\/sup><\/p>\n<p><span class=\"legal_copy\">The Vascular Quality of Life Questionnaire is a survey used to determine health related quality of life (HRQoL) in patients with peripheral arterial disease (PAD). Each attribute is scored 1-4, a higher value indicates better health status. The sum of each individual attribute score is used to generate a total quality of life score.<\/span><\/p>\n<p><span class=\"legal_copy\">1: Armstrong E, VIVA 2025.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"leadership\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_1e417b6ac8dda84d4e42d327df3136e6\" class=\"block block--attribution \" role=\"region\" aria-labelledby=\"block_1e417b6ac8dda84d4e42d327df3136e6-heading\" aria-describedby=\"block_1e417b6ac8dda84d4e42d327df3136e6-desc\">\n\t<div class=\"container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"block_1e417b6ac8dda84d4e42d327df3136e6-heading\" class=\"heading\">\n\t\t\t\t\tStudy Leadership \t\t\t\t<\/h3>\n\t\t\t\t\t\t<p id=\"block_1e417b6ac8dda84d4e42d327df3136e6-desc\" class=\"sr-only\">This section contains attributions including profile pictures, titles, descriptions, and Twitter handles.<\/p>\n\n\t\t\t\t\t\t\t<ul class=\"attributions-container\" role=\"list\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Venita Chandra, MD <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Clinical Associate Professor of Surgery, Associate Program Director \u2013 Vascular Surgery, Medical Director \r\nStanford Advanced Wound Center <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Ehrin Armstrong, MD <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Medical Director, Aurora Denver Cardiology Associates, Swedish Medical Center<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n<section id=\"block_abd9beab0f6797a730bec2f38d6e1686\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors \">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">More Shockwave Peripheral IVL Studies <\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6686\" aria-describedby=\"post-category-6686 post-excerpt-6686\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6686\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/btk-ii\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT BTK II\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6686\">\n\t\t\t\t\t\tGlobal prospective, multi-center, single-arm  study assessing the safety and effectiveness of Shockwave peripheral IVL in treating long, calcified BTK lesions. \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6686\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6554\" aria-describedby=\"post-category-6554 post-excerpt-6554\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6554\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/pad-iii-rct\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Randomized Clinical Trial\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6554\">\n\t\t\t\t\t\tThe largest-ever randomized clinical study of Shockwave peripheral IVL treatment in severely calcified peripheral lesions, out to 24 months.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6554\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6527\" aria-describedby=\"post-category-6527 post-excerpt-6527\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6527\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/pad-iii-os\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Observational Study\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6527\">\n\t\t\t\t\t\tThe largest prospective real-world evidence for the treatment of complex, heavily calcified peripheral arterial disease (PAD).\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6527\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>\n\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This DISRUPT BTK II sub-analysis focuses on results from the CLTI cohort at 12-months.<\/p>\n","protected":false},"featured_media":13021,"template":"","format":[],"meta":{"_acf_changed":true,"content-type":""},"disease-state":[151,167],"product-tag":[283,291],"specialty":[295,328,332,336,344],"technology":[324],"class_list":["post-13041","clinical-evidence","type-clinical-evidence","status-publish","has-post-thumbnail","hentry","disease-state-below-the-knee-btk","disease-state-peripheral-artery-disease-en-uk","product-tag-shockwave-m5","product-tag-shockwave-s4-en-uk","specialty-fellows-residents-en-uk","specialty-interventional-cardiologists-en-uk","specialty-interventional-radiologists-en-uk","specialty-nurses-technologists-en-uk","specialty-vascular-surgeons-en-uk","technology-peripheral-ivl-en-uk"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/clinical-evidence\/13041","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/clinical-evidence"}],"about":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/types\/clinical-evidence"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media\/13021"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media?parent=13041"}],"wp:term":[{"taxonomy":"disease-state","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/disease-state?post=13041"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/format?post=13041"},{"taxonomy":"product-tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/product-tag?post=13041"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/specialty?post=13041"},{"taxonomy":"technology","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/technology?post=13041"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}