{"id":13041,"date":"2025-11-03T14:00:00","date_gmt":"2025-11-03T20:00:00","guid":{"rendered":"https:\/\/shockwavemedical.com\/?post_type=clinical-evidence&#038;p=13041"},"modified":"2026-10-06T13:19:33","modified_gmt":"2026-10-06T18:19:33","slug":"disrupt-btk-ii-clti-cohort-analysis","status":"publish","type":"clinical-evidence","link":"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/disrupt-btk-ii-clti-cohort-analysis\/","title":{"rendered":"DISRUPT BTK II CLTI Cohort Analysis"},"content":{"rendered":"\n\n\n<section id=\"block_e5a45e46526556b076d6ec9f2b8f150a\" class=\"block block--primary-header u-darkMode u-bgColor_primary shockwave\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Background-Pulses.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">DISRUPT BTK II CLTI Cohort Analysis<\/h1>\n\t\t\t<h3 class=\"sub-heading\">Establishing a new benchmark for patients with CLTI: New data confirm Shockwave IVL\u2019s continued impact on patients with CLTI at 24 months. DISRUPT BTK II assessed the continued safety and effectiveness of the Shockwave Peripheral IVL System for the treatment of calcified, stenotic lesions in below-the-knee (BTK) arteries. This sub-analysis focuses on results from the patients with CLTI enrolled in the study.<\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2025\/11\/DISRUPT-BTK-II-CLTI-Cohort-Analysis-Hero-Logo.png\" alt=\"DISRUPT BTK II CLTI Cohort Analysis logo\" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t<\/div>\n<\/section>\n\n\n<section id=\"block_6f49c5fb23325b69eee5ff72203793a1\" class=\"block block--content-3-or-4-up text_colors shockwave\" aria-labelledby=\"section-heading-block_6f49c5fb23325b69eee5ff72203793a1\">\n\t<div class=\"container\">\n\n\t\t<!-- Header -->\n\t\t\t\t\t<header class=\"heading-row\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"section-heading-block_6f49c5fb23325b69eee5ff72203793a1\" class=\"optional-heading\">\n\t\t\t\t\t\tCLTI Cohort Key Findings\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/header>\n\t\t\n\t\t<!-- Cards Section -->\n\t\t<ul class=\"cards three-cards\" role=\"list\">\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Establishing a new benchmark in CLTI<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">Shockwave IVL delivers outcomes, out to two years, that set a new benchmark for success in the minimally invasive treatment of patients with CLTI with calcified BTK lesions.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Demonstrating clinical durability<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">DISRUPT BTK II 24-month outcomes show continued durability of Shockwave IVL for calcified BTK treatment, demonstrating sustained clinical benefit in a complex CLTI population.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Reinforcing Shockwave IVL as a frontline strategy<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-description small_body\">The 24-month outcomes further establish Shockwave IVL as a frontline calcium modification strategy for patients with complex BTK lesions.<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_2e66075e4c062754ce241ec6defdc6cf\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">Chandra V, Two-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2026.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"design\" class=\"block block--study-design-patient-chars shockwave\" role=\"region\" aria-labelledby=\"design-heading\">\n\t<div class=\"container\">\n\t\t\t\t\t<div class=\"heading-row wysiwyg_styles\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"design-heading\" class=\"heading\">\n\t\t\t\t\t\tDISRUPT BTK II Study Design\t\t\t\t\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"columns wysiwyg_styles\" aria-label=\"Study Design Columns\">\n\t\t\t<div class=\"columns-2-and-3\">\n\t\t\t\t<div class=\"column-2\">\n\t\t\t\t\t<p><b><span data-contrast=\"auto\">Objective<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p>Assess the continued safety and effectiveness of the Shockwave Medical Peripheral IVL System for the treatment of calcified, stenotic lesions in BTK arteries. Products included Shockwave M5+ and Shockwave S4.<\/p>\n<p><strong>Key Inclusion Criteria<\/strong><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"5\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":360,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Rutherford classification (RC) 3-5, RC 3 capped at 20% of enrolled patients<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"5\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":360,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Moderate-severe calcification*<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"5\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":360,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Up to two BTK lesions \u2264 200 mm in length<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/li>\n<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-3\">\n\t\t\t\t\t<p><b><span data-contrast=\"auto\">Primary Safety Endpoint<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Major adverse limb events (MALE) or post-operative death (POD) at 30 days<\/span><\/p>\n<p><b><span data-contrast=\"auto\">Primary Effectiveness Endpoint<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Procedural success, defined as <\/span><b><span data-contrast=\"auto\">\u2264 50%<\/span><\/b><span data-contrast=\"auto\"> residual stenosis for all treated target lesions without serious angiographic complications<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Additional analysis to include lesions with <\/span><b><span data-contrast=\"auto\">\u2264 30%<\/span><\/b><span data-contrast=\"auto\"> residual stenosis without angiographic complications<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p>Independent Clinical Events Committee (CEC), Angiographic Core Laboratory, and Duplex Ultrasound Core Laboratory<\/p>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"column-1\">\n\t\t\t\t<div class=\"column-1-content\">\n\t\t\t\t\t<div class=\"column-1-content-top\">\n\t\t\t\t\t\tDISRUPT BTK II, the largest prospective study of real-world, complex patients with moderate to severe calcified BTK disease, now demonstrates durable outcomes through 24 months.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"column-1-content-bottom\">\n\t\t\t\t\t\tNo other calcium modification technology has been evaluated in a population this challenging, setting Shockwave IVL as a benchmark for CLTI care.\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-1-arrow\" aria-hidden=\"true\" aria-label=\"Arrow pointing downwards to indicate result\"><i class=\"fa-regular fa-arrow-down\"><\/i><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n\n<section id=\"block_2538691cd1e0f297e704547e03cf4d75\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">*Presence of fluoroscopic evidence of calcification by PARC (Peripheral Academic Research Consortium) definition: 1) on parallel sides of the vessel and 2) extending > 50% the length of the lesion if lesion is \u2265 50 mm in length; or extending for minimum of 20 mm if lesion is < 50 mm in length.\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n<section id=\"demographics\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors has-stat-callout on-dark\">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">Full Cohort By the Numbers<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"on-dark btn--primary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/btk-ii\/\" target=\"_self\" aria-label=\"DISRUPT BTK II - link to page\" >DISRUPT BTK II<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\"on-dark btn--primary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/btk-ii\/\" target=\"_self\" aria-label=\"DISRUPT BTK II - link to page\" >DISRUPT BTK II<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\n<section id=\"demographics\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-0\" role=\"listitem\" aria-labelledby=\"demographics-card-0-number\" aria-describedby=\"demographics-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-0-number\">250<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-0-description\">\n\t\t\t\t\t\tPatients\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-1\" role=\"listitem\" aria-labelledby=\"demographics-card-1-number\" aria-describedby=\"demographics-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-1-number\">305<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-1-description\">\n\t\t\t\t\t\tLesions\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-2\" role=\"listitem\" aria-labelledby=\"demographics-card-2-number\" aria-describedby=\"demographics-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-2-number\">38<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-2-description\">\n\t\t\t\t\t\tGlobal sites\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"demographics-card-3\" role=\"listitem\" aria-labelledby=\"demographics-card-3-number\" aria-describedby=\"demographics-card-3-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"demographics-card-3-number\">2<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"demographics-card-3-description\">\n\t\t\t\t\t\tYear follow-up\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t<\/ul>\n<\/section>\n\n\n\n<section id=\"block_7f1932e03dc2a0ed9a729eef6903a9e7\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><img decoding=\"async\" class=\"aligncenter wp-image-14867 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-Follow-up-Breakdown-graphic.png\" alt=\"\" width=\"2000\" height=\"568\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-Follow-up-Breakdown-graphic.png 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-Follow-up-Breakdown-graphic-300x85.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-Follow-up-Breakdown-graphic-1024x291.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-Follow-up-Breakdown-graphic-768x218.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-Follow-up-Breakdown-graphic-1536x436.png 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/568;\" \/><\/p>\n<p><span class=\"legal_copy\">Chandra V, Two-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2026.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_5fecfd9fe700f52a95c96b98d44e89f6\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_5fecfd9fe700f52a95c96b98d44e89f6\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 30px; --aboveMobile: 20px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n<section id=\"block_df4a0a4f44f04b203b629abf0d74a647\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors has-stat-callout on-dark\">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">CLTI Cohort By the Numbers<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\n\t\t\t\n<section id=\"block_df4a0a4f44f04b203b629abf0d74a647\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_df4a0a4f44f04b203b629abf0d74a647-card-0\" role=\"listitem\" aria-labelledby=\"block_df4a0a4f44f04b203b629abf0d74a647-card-0-number\" aria-describedby=\"block_df4a0a4f44f04b203b629abf0d74a647-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_df4a0a4f44f04b203b629abf0d74a647-card-0-number\">200<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_df4a0a4f44f04b203b629abf0d74a647-card-0-description\">\n\t\t\t\t\t\tPatients\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_df4a0a4f44f04b203b629abf0d74a647-card-1\" role=\"listitem\" aria-labelledby=\"block_df4a0a4f44f04b203b629abf0d74a647-card-1-number\" aria-describedby=\"block_df4a0a4f44f04b203b629abf0d74a647-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_df4a0a4f44f04b203b629abf0d74a647-card-1-number\">245<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_df4a0a4f44f04b203b629abf0d74a647-card-1-description\">\n\t\t\t\t\t\tLesions\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t<\/ul>\n<\/section>\n\n\n\n<!-- BLOCK CONTENT -->\n<section id=\"block_7aa02b379de4de2fce04afc27310951c\"  class=\"block block--section \">\n\t<div class=\"container\">\n\t\t\n\n<section id=\"block_b11c01fa4ff254dfa4476fb0be81c7fc\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>CLTI Cohort Baseline Demographics<\/h2>\n<h3>Rutherford Category<\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_2f24960eb7261828811cd84676993917\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_2f24960eb7261828811cd84676993917-card-0\" role=\"listitem\" aria-labelledby=\"block_2f24960eb7261828811cd84676993917-card-0-number\" aria-describedby=\"block_2f24960eb7261828811cd84676993917-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_2f24960eb7261828811cd84676993917-card-0-number\">71<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_2f24960eb7261828811cd84676993917-card-0-description\">\n\t\t\t\t\t\tRC 5, minor tissue loss<sup>2<\/sup>*\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_2f24960eb7261828811cd84676993917-card-1\" role=\"listitem\" aria-labelledby=\"block_2f24960eb7261828811cd84676993917-card-1-number\" aria-describedby=\"block_2f24960eb7261828811cd84676993917-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_2f24960eb7261828811cd84676993917-card-1-number\">29<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_2f24960eb7261828811cd84676993917-card-1-description\">\n\t\t\t\t\t\tRC 4, ischemic rest pain<sup>2<\/sup>**\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_34701a0da1c40105060ec1ee8163ec6c\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Medical History<\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_8f33751ca60d0dc60b8001c4d4d963ea\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0\" role=\"listitem\" aria-labelledby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-number\" aria-describedby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-number\">73<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-0-description\">\n\t\t\t\t\t\tPatients had wounds at baseline<sup>2<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1\" role=\"listitem\" aria-labelledby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-number\" aria-describedby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-number\">18<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-1-description\">\n\t\t\t\t\t\tHemodialysis-dependent<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2\" role=\"listitem\" aria-labelledby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-number\" aria-describedby=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-number\">77<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_8f33751ca60d0dc60b8001c4d4d963ea-card-2-description\">\n\t\t\t\t\t\tDiabetes mellitus<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_a71625c93f51544764db453978fd4be5\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Lesions<\/h3>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_845b864885b0124f615e2ba8b31c16f4\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-0\" role=\"listitem\" aria-labelledby=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-number\" aria-describedby=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-number\">86<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-0-description\">\n\t\t\t\t\t\tModerate-severe Ca++<sup>1\u2020<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-1\" role=\"listitem\" aria-labelledby=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-number\" aria-describedby=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-number\">80<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>mm<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-1-description\">\n\t\t\t\t\t\tMean lesion length<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-2\" role=\"listitem\" aria-labelledby=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-number\" aria-describedby=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-number\">31<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_845b864885b0124f615e2ba8b31c16f4-card-2-description\">\n\t\t\t\t\t\tChronic total occlusions (CTOs)<sup>1<\/sup>\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_ce4e25fc71cc28a3f044da24a1b10d29\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">1: Armstrong E, One-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2025.<br \/>\n2: Based on analysis of the CLTI cohort enrolled in the BTK II study.<br \/>\n*Per limb 143\/201 | **Per limb 59\/201 | <sup>\u2020<\/sup>PARC Definition<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"results\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_834d2f5250fa6b6f7710b7a49da4e0c5\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Results and conclusion<\/h2>\n<h3>Clinical Procedural Insights in a CLTI Cohort<\/h3>\n<p>In a challenging patient cohort, IVL was shown to be a safe and effective treatment of challenging calcific BTK lesions with minimal need for provisional stenting.<\/p>\n<h4 style=\"text-align: center;\">CONFIRMED SAFETY<\/h4>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">Total Serious Angiographic Complications Post-IVL<sup>2<\/sup><\/td>\n<td style=\"width: 50%;\">Total Serious Angiographic Complications at Final<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">2.3%<\/td>\n<td style=\"width: 50%;\">1.3%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h4 style=\"text-align: center;\">CONFIRMED EFFECTIVENESS<\/h4>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">\u00a0Average Residual Stenosis Post-IVL<sup>2<\/sup><\/td>\n<td style=\"width: 50%;\">Average Residual Stenosis at Final<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">30.0%<\/td>\n<td style=\"width: 50%;\">25.7%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<h4 style=\"text-align: center;\">MINIMAL PROVISIONAL STENTING<\/h4>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%;\">Stent\/Tack Implant Total<sup>2<\/sup><\/td>\n<td style=\"width: 50%;\">Provisional Stent\/Tack Implant<sup>2<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%;\">5.7%<\/td>\n<td style=\"width: 50%;\">2.8%*<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">*Remaining Stent\/Tack implants were part of physicians\u2019 standard algorithm.<br \/>\n1: Armstrong E, One-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2025.<br \/>\n2: Based on analysis of the CLTI cohort enrolled in the BTK II study.<br \/>\n<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_164090ff1f7db4648d7736209834f65e\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Freedom from CD-TLR at 24 Months<\/h3>\n<p>24-month outcomes confirm the durability of Shockwave IVL\u2019s clinical outcomes in complex calcified BTK disease.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-14859 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-CD-TLR-data-graph.png\" alt=\"\" width=\"2000\" height=\"715\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-CD-TLR-data-graph.png 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-CD-TLR-data-graph-300x107.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-CD-TLR-data-graph-1024x366.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-CD-TLR-data-graph-768x275.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-CD-TLR-data-graph-1536x549.png 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/715;\" \/><\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 50%; text-align: center;\">Rutherford Category<\/td>\n<td style=\"width: 50%; text-align: center;\">Freedom from CD-TLR at 24 Months<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; text-align: left;\">Full Cohort (n=250)<\/td>\n<td style=\"width: 50%; text-align: center;\">81.0%<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; text-align: left;\">RC 3 (n=50)<\/td>\n<td style=\"width: 50%; text-align: center;\">87.3%<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; text-align: left;\">CLTI Cohort (n=200)<\/td>\n<td style=\"width: 50%; text-align: center;\">79.2%<sup>1<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; padding-left: 40px; text-align: left;\">RC 4 (n=57)<\/td>\n<td style=\"width: 50%; text-align: center;\">79.6%<sup>2<\/sup><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 50%; padding-left: 40px; text-align: left;\">RC 5 (n=143)<\/td>\n<td style=\"width: 50%; text-align: center;\">79.3%<sup>2<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">1: Chandra V, Two-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2026.<br \/>\n2: Data on file at Shockwave Medical.<br \/>\nClinically driven target revascularization (CD-TLR).<br \/>\nKaplan Meier (KM) is an analysis that uses probability to capture patients lost to follow-up.<br \/>\nFreedom from CD-TLR analysis excluded patients with above the ankle amputation of target limb.<\/span><\/p>\n<p>\u00a0<\/p>\n<h3>Freedom from Major Amputation at 24 Months<\/h3>\n<p>At 24 months, Shockwave IVL supports limb preservation and sustained symptom improvement in high-risk patients with CLTI.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-14863 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-major-amputation-data-graph.png\" alt=\"\" width=\"2000\" height=\"715\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-major-amputation-data-graph.png 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-major-amputation-data-graph-300x107.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-major-amputation-data-graph-1024x366.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-major-amputation-data-graph-768x275.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-FF-major-amputation-data-graph-1536x549.png 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/715;\" \/><\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 144px;\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: center;\">Rutherford Category<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">Freedom from Major Amputation at 24 Months<\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: left;\">Full Cohort (n=250)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">94.8%<sup>1<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: left;\">RC 3 (n=50)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">100%<sup>1<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; text-align: left;\">CLTI Cohort (n=200)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">93.3%<sup>1<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; padding-left: 40px; text-align: left;\">RC 4 (n=57)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">98.1%<sup>2<\/sup><\/td>\n<\/tr>\n<tr style=\"height: 24px;\">\n<td style=\"width: 50%; height: 24px; padding-left: 40px; text-align: left;\">RC 5 (n=143)<\/td>\n<td style=\"width: 50%; height: 24px; text-align: center;\">91.2%<sup>2<\/sup><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legal_copy\">1: Chandra V, Two-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2026.<br \/>\n2: Data on file at Shockwave Medical.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_a4b6c29a6f5854e08a9618ecb42a51ab\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone shockwave container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h3>Rutherford Classification (RC) Change at 24 Months<\/h3>\n<p>24-month outcomes show continued durability of Shockwave IVL for calcified BTK treatment, demonstrating sustained clinical benefit in a complex CLTI population.<\/p>\n<ul>\n<li>Of the patients remaining at 24 months, <strong>82% were no longer CLTI<\/strong><sup>1<\/sup><\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-14871 size-full lazyload\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-data-graph-final.png\" alt=\"\" width=\"2000\" height=\"605\" data-srcset=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-data-graph-final.png 2000w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-data-graph-final-300x91.png 300w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-data-graph-final-1024x310.png 1024w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-data-graph-final-768x232.png 768w, https:\/\/shockwavemedical.com\/wp-content\/uploads\/2026\/10\/BTK-II-CLTI-Cohort-24-month-RC-data-graph-final-1536x465.png 1536w\" data-sizes=\"(max-width: 2000px) 100vw, 2000px\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2000px; --smush-placeholder-aspect-ratio: 2000\/605;\" \/><\/p>\n<p><span class=\"legal_copy\">1: Chandra V, Two-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2026.<\/span><\/p>\n<p>\u00a0<\/p>\n<h3>Quality of Life at 24 Months<\/h3>\n<p>Shockwave IVL facilitates sustained symptom improvement for patients with CLTI through 24 months.<\/p>\n<table style=\"border-collapse: collapse; width: 100%; height: 126px;\">\n<tbody>\n<tr style=\"height: 24px;\">\n<td style=\"width: 12.5%; height: 126px;\" rowspan=\"3\">Breakdown by Attribute<\/td>\n<td style=\"width: 12.5%; height: 24px;\">VascuQoL-6 Attribute<\/td>\n<td style=\"width: 12.5%; height: 24px;\">Activity<\/td>\n<td style=\"width: 12.5%; height: 24px;\">Tired<\/td>\n<td style=\"width: 12.5%; height: 24px;\">Walk<\/td>\n<td style=\"width: 12.5%; height: 24px;\">Concern<\/td>\n<td style=\"width: 12.5%; height: 24px;\">Social<\/td>\n<td style=\"width: 12.5%; height: 24px;\">Pain<\/td>\n<\/tr>\n<tr style=\"height: 51px;\">\n<td style=\"width: 12.5%; height: 51px;\"><strong>Average Score 24 Months<sup>1<\/sup><\/strong><\/td>\n<td style=\"width: 12.5%; height: 51px;\">3<\/td>\n<td style=\"width: 12.5%; height: 51px;\">2.8<\/td>\n<td style=\"width: 12.5%; height: 51px;\">3.1<\/td>\n<td style=\"width: 12.5%; height: 51px;\">3.1<\/td>\n<td style=\"width: 12.5%; height: 51px;\">3.3<\/td>\n<td style=\"width: 12.5%; height: 51px;\">2.9<\/td>\n<\/tr>\n<tr style=\"height: 51px;\">\n<td style=\"width: 12.5%; height: 51px;\"><strong>Average Score Baseline<sup>2<\/sup><\/strong><\/td>\n<td style=\"width: 12.5%; height: 51px;\">1.9<\/td>\n<td style=\"width: 12.5%; height: 51px;\">2.0<\/td>\n<td style=\"width: 12.5%; height: 51px;\">2.3<\/td>\n<td style=\"width: 12.5%; height: 51px;\">1.7<\/td>\n<td style=\"width: 12.5%; height: 51px;\">2.3<\/td>\n<td style=\"width: 12.5%; height: 51px;\">1.8<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<p>Total VascuQoL-6 Score (CLTI) at 24 months significantly improved from baseline (P-Value: p<0.001). Total at 24 months was 18.1 \u00b1 4.6 and total at baseline was 11.9 \u00b1 4.0.<sup>1,2<\/sup><\/p>\n<p><span class=\"legal_copy\">The Vascular Quality of Life Questionnaire is a survey used to determine health related quality of life (HRQoL) in patients with peripheral arterial disease (PAD). Each attribute is scored 1-4, a higher value indicates better health status. The sum of each individual attribute score is used to generate a total quality of life score.<\/span><\/p>\n<p><span class=\"legal_copy\">1: Data on file at Shockwave Medical.<br \/>\n2: Armstrong E, One-Year Outcomes from the Disrupt PAD BTK II Study. VIVA. Las Vegas, NV; 2025.<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"leadership\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_1e417b6ac8dda84d4e42d327df3136e6\" class=\"block block--attribution \" role=\"region\" aria-labelledby=\"block_1e417b6ac8dda84d4e42d327df3136e6-heading\" aria-describedby=\"block_1e417b6ac8dda84d4e42d327df3136e6-desc\">\n\t<div class=\"container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"block_1e417b6ac8dda84d4e42d327df3136e6-heading\" class=\"heading\">\n\t\t\t\t\tStudy Leadership \t\t\t\t<\/h3>\n\t\t\t\t\t\t<p id=\"block_1e417b6ac8dda84d4e42d327df3136e6-desc\" class=\"sr-only\">This section contains attributions including profile pictures, titles, descriptions, and Twitter handles.<\/p>\n\n\t\t\t\t\t\t\t<ul class=\"attributions-container\" role=\"list\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Venita Chandra, MD <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Clinical Associate Professor of Surgery, Associate Program Director \u2013 Vascular Surgery, Medical Director \r\nStanford Advanced Wound Center <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Ehrin Armstrong, MD <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Medical Director, Aurora Denver Cardiology Associates, Swedish Medical Center<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n<section id=\"block_abd9beab0f6797a730bec2f38d6e1686\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors \">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">More Shockwave Peripheral IVL Studies <\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6686\" aria-describedby=\"post-category-6686 post-excerpt-6686\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6686\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/btk-ii\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT BTK II\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6686\">\n\t\t\t\t\t\tGlobal prospective, multi-center, single-arm  study assessing the safety and effectiveness of Shockwave peripheral IVL in treating long, calcified BTK lesions. \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6686\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6554\" aria-describedby=\"post-category-6554 post-excerpt-6554\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6554\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/pad-iii-rct\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Randomized Clinical Trial\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6554\">\n\t\t\t\t\t\tThe largest-ever randomized clinical study of Shockwave peripheral IVL treatment in severely calcified peripheral lesions, out to 24 months.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6554\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6527\" aria-describedby=\"post-category-6527 post-excerpt-6527\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6527\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/pad-iii-os\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Observational Study\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6527\">\n\t\t\t\t\t\tThe largest prospective real-world evidence for the treatment of complex, heavily calcified peripheral arterial disease (PAD).\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6527\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>\n\n\n<section\n\tid=\"block_64f73ab1f31757ce6b3d33a72db14c76\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This DISRUPT BTK II sub-analysis focuses on results from the CLTI cohort at 12-months.<\/p>\n","protected":false},"featured_media":13021,"template":"","format":[],"meta":{"_acf_changed":true,"content-type":""},"disease-state":[151,167],"product-tag":[283,291],"specialty":[295,328,332,336,344],"technology":[324],"class_list":["post-13041","clinical-evidence","type-clinical-evidence","status-publish","has-post-thumbnail","hentry","disease-state-below-the-knee-btk","disease-state-peripheral-artery-disease-en-uk","product-tag-shockwave-m5","product-tag-shockwave-s4-en-uk","specialty-fellows-residents-en-uk","specialty-interventional-cardiologists-en-uk","specialty-interventional-radiologists-en-uk","specialty-nurses-technologists-en-uk","specialty-vascular-surgeons-en-uk","technology-peripheral-ivl-en-uk"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/clinical-evidence\/13041","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/clinical-evidence"}],"about":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/types\/clinical-evidence"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media\/13021"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media?parent=13041"}],"wp:term":[{"taxonomy":"disease-state","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/disease-state?post=13041"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/format?post=13041"},{"taxonomy":"product-tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/product-tag?post=13041"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/specialty?post=13041"},{"taxonomy":"technology","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/technology?post=13041"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}