{"id":6607,"date":"2017-09-19T15:44:00","date_gmt":"2017-09-19T20:44:00","guid":{"rendered":"https:\/\/shockwavemedical.com\/clinical-evidence\/disrupt-btk\/"},"modified":"2025-01-04T10:42:49","modified_gmt":"2025-01-04T16:42:49","slug":"btk","status":"publish","type":"clinical-evidence","link":"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/btk\/","title":{"rendered":"DISRUPT BTK"},"content":{"rendered":"\n<section id=\"block_6afa1e593343eaf48defbf9a2e9aeb66\" class=\"block block--primary-header u-darkMode u-bgColor_primary\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Background-Pulses.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">DISRUPT BTK <\/h1>\n\t\t\t<h3 class=\"sub-heading\">Post-market, European study to assess the safety and performance of Shockwave Intravascular Lithotripsy (IVL) as a standalone therapy in heavily calcified infrapopliteal lesions out to 30 days. <\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/DISRUPT-BTK-clinical-hero-image.png\" alt=\"DISRUPT BTK logo\" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t\t\t<div class=\"mobile-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Clinical-Hero-Images-mobile-07.png\" alt=\"DISRUPT BTK logo\" role=\"img\" aria-label=\"Foreground image for mobile\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 814px; --smush-placeholder-aspect-ratio: 814\/467;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_39d5bec96455bde6c81403ccc5677c7e\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_a66e3890449579c59e9271fbcec310d0\" class=\"block block--attribution \" role=\"region\" aria-labelledby=\"block_a66e3890449579c59e9271fbcec310d0-heading\" aria-describedby=\"block_a66e3890449579c59e9271fbcec310d0-desc\">\n\t<div class=\"container\">\n\t\t<div class=\"container-inner\">\n\t\t\t\t\t\t\t<h3 id=\"block_a66e3890449579c59e9271fbcec310d0-heading\" class=\"heading\">\n\t\t\t\t\tStudy Leadership \t\t\t\t<\/h3>\n\t\t\t\t\t\t<p id=\"block_a66e3890449579c59e9271fbcec310d0-desc\" class=\"sr-only\">This section contains attributions including profile pictures, titles, descriptions, and Twitter handles.<\/p>\n\n\t\t\t\t\t\t\t<ul class=\"attributions-container\" role=\"list\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Marianne Brodmann, MD <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Medical University Graz, Austria\u202f <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Andrew Holden, MD <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Auckland City Hospital, Auckland, New Zealand <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"attribution\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"details\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"title\">Thomas Zeller, MD  <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"description\">Universit\u00e4ts-Herzzentrum Freiberg-Bad Krozingen, Bad Krozingen, Germany <\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_3d0badffe0f11e6fd98c382a14799216\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 0px; --aboveMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_d0c8b208f6f0b5a2a354db636735210c\" class=\"block block--study-design-patient-chars \" role=\"region\" aria-labelledby=\"block_d0c8b208f6f0b5a2a354db636735210c-heading\">\n\t<div class=\"container\">\n\t\t\t\t\t<div class=\"heading-row wysiwyg_styles\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"block_d0c8b208f6f0b5a2a354db636735210c-heading\" class=\"heading\">\n\t\t\t\t\t\tStudy Design and Patient Characteristics \t\t\t\t\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"columns wysiwyg_styles\" aria-label=\"Study Design Columns\">\n\t\t\t<div class=\"columns-2-and-3\">\n\t\t\t\t<div class=\"column-2\">\n\t\t\t\t\t<p><b><span data-contrast=\"auto\">Objective<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Post-market, European study to assess the safety and performance of Shockwave IVL as standalone therapy in heavily calcified infrapopliteal lesions out to 30 days.<\/span><span data-ccp-props=\"{}\"><br \/>\n<\/span><\/p>\n<p>\u00a0<\/p>\n<p><b><span data-contrast=\"auto\">Primary Safety Endpoint<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Composite of major adverse events (MAE), defined as death, myocardial infarction, need for emergency surgical revascularization of the target limb, or amputation of the target limb.\u202f<\/span><span data-ccp-props=\"{}\"><br \/>\n<\/span><\/p>\n<p>\u00a0<\/p>\n<p><b><span data-contrast=\"auto\">Secondary Endpoint<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Procedural success, defined as the ability of the Shockwave peripheral IVL system to achieve \u226450% residual diameter stenosis.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-3\">\n\t\t\t\t\t<p><b><span data-contrast=\"auto\">Patient Characteristics Summary<\/span><\/b><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<ul>\n<li><span data-contrast=\"auto\">\u202f20 patients from three sites<\/span><\/li>\n<li><span data-contrast=\"auto\">\u202f100% moderately\/severely\u202fcalcified lesions<\/span><\/li>\n<li><span data-contrast=\"auto\"> 75% Rutherford Category 5<\/span><\/li>\n<\/ul>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"column-1\">\n\t\t\t\t<div class=\"column-1-content\">\n\t\t\t\t\t<div class=\"column-1-content-top\">\n\t\t\t\t\t\t>50% infrapopliteal stenosis <150 mm long, a target vessel diameter of 2.5 to 3.5 mm, Rutherford category 3 to 5 ischemia, and moderate to severe calcification \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"column-1-content-bottom\">\n\t\t\t\t\t\t100% freedom from clinically driven target lesion revascularization (CD TLR) at 30 days, 0% MAE at 30 days \t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"column-1-arrow\" aria-hidden=\"true\" aria-label=\"Arrow pointing downwards to indicate result\"><i class=\"fa-regular fa-arrow-down\"><\/i><\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<div class=\"countries-section text_colors\">\n\t\t\t\t\t\t\t\t\t<div class=\"countries-header\">\n\t\t\t\t\t\t<h3 id=\"block_d0c8b208f6f0b5a2a354db636735210c-countries-heading\">\n\t\t\t\t\t\t\tCountries Included in Study\u202f \t\t\t\t\t\t<\/h3>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<ul class=\"countries\" aria-labelledby=\"block_d0c8b208f6f0b5a2a354db636735210c-countries-heading\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"countries-country\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/themes\/shockwave-med\/assets\/dist\/imgs\/country-flags\/at.png\"\n\t\t\t\t\t\t\t\t\talt=\"Flag of Austria\"\n\t\t\t\t\t\t\t\t\tclass=\"country-flag lazyload\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2560px; --smush-placeholder-aspect-ratio: 2560\/1707;\" \/>\n\t\t\t\t\t\t\t\t<span class=\"country-name small_body\">Austria<\/span>\n\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"countries-country\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/themes\/shockwave-med\/assets\/dist\/imgs\/country-flags\/de.png\"\n\t\t\t\t\t\t\t\t\talt=\"Flag of Germany\"\n\t\t\t\t\t\t\t\t\tclass=\"country-flag lazyload\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2560px; --smush-placeholder-aspect-ratio: 2560\/1536;\" \/>\n\t\t\t\t\t\t\t\t<span class=\"country-name small_body\">Germany<\/span>\n\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"countries-country\">\n\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/themes\/shockwave-med\/assets\/dist\/imgs\/country-flags\/nz.png\"\n\t\t\t\t\t\t\t\t\talt=\"Flag of New Zealand\"\n\t\t\t\t\t\t\t\t\tclass=\"country-flag lazyload\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2560px; --smush-placeholder-aspect-ratio: 2560\/1280;\" \/>\n\t\t\t\t\t\t\t\t<span class=\"country-name small_body\">New Zealand<\/span>\n\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n\n<section id=\"block_50630639a708764436ccf9b8c3749768\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">*Core Lab & CEC adjudicated.\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_39d5bec96455bde6c81403ccc5677c7e\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_ac92e23f7e6303338d498a6da5653e74\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2><span class=\"TextRun SCXW112619253 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW112619253 BCX0\">Compelling Safety <\/span><span class=\"NormalTextRun SCXW112619253 BCX0\">and<\/span><span class=\"NormalTextRun SCXW112619253 BCX0\"> Performance in Severely Calcified Lesions<\/span><\/span><span class=\"EOP SCXW112619253 BCX0\" data-ccp-props=\"{}\">\u00a0<\/span><\/h2>\n\t<\/div>\n\t<\/section>\n\n\n<section id=\"block_049f0b2b8b88aaae3461ecc2068f13f9\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-0\" role=\"listitem\" aria-labelledby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-0-number\" aria-describedby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-0-number\">95<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-0-description\">\n\t\t\t\t\t\tProcedural success\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-1\" role=\"listitem\" aria-labelledby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-1-number\" aria-describedby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-1-number\">0<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-1-description\">\n\t\t\t\t\t\tPerforations, embolization, slow\/no reflow, abrupt closure\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-2\" role=\"listitem\" aria-labelledby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-2-number\" aria-describedby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-2-number\">26<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-2-description\">\n\t\t\t\t\t\tFinal residual stenosis with an acute gain of 1.5 mm\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-3\" role=\"listitem\" aria-labelledby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-3-number\" aria-describedby=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-3-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-3-number\">0<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span>%<\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_049f0b2b8b88aaae3461ecc2068f13f9-card-3-description\">\n\t\t\t\t\t\tMajor adverse event at 30 days\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\n\n\n<section id=\"block_50630639a708764436ccf9b8c3749768\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p><span class=\"legal_copy\">*Core Lab & CEC adjudicated.\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section id=\"block_2919bb8f30c8b129f89e0928a66c4052\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors \">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">More Shockwave Peripheral IVL Studies <\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/\" target=\"_self\" aria-label=\"See All Clinical Evidence - link to page\" >See All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6686\" aria-describedby=\"post-category-6686 post-excerpt-6686\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6686\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/btk-ii\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT BTK II\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6686\">\n\t\t\t\t\t\tGlobal prospective, multi-center, single-arm  study assessing the safety and effectiveness of Shockwave peripheral IVL in treating long, calcified BTK lesions. \t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6686\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6554\" aria-describedby=\"post-category-6554 post-excerpt-6554\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6554\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/pad-iii-rct\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Randomized Clinical Trial\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6554\">\n\t\t\t\t\t\tThe largest-ever randomized clinical study of Shockwave peripheral IVL treatment in severely calcified peripheral lesions, out to 24 months.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6554\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-6527\" aria-describedby=\"post-category-6527 post-excerpt-6527\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-6527\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/pad-iii-os\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT PAD III Observational Study\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-6527\">\n\t\t\t\t\t\tThe largest prospective real-world evidence for the treatment of complex, heavily calcified peripheral arterial disease (PAD).\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-6527\">\n\t\t\t\t\t\tPeripheral IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>\n\n\n<section\n\tid=\"block_39d5bec96455bde6c81403ccc5677c7e\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Post-market, European study to assess the safety and performance of Shockwave IVL as a standalone therapy in heavily calcified infrapopliteal lesions out to 30 days.<\/p>\n","protected":false},"featured_media":4004,"template":"","format":[],"meta":{"_acf_changed":true,"content-type":""},"disease-state":[151,167],"product-tag":[283,291],"specialty":[295,328,332,336,344],"technology":[324],"class_list":["post-6607","clinical-evidence","type-clinical-evidence","status-publish","has-post-thumbnail","hentry","disease-state-below-the-knee-btk","disease-state-peripheral-artery-disease-en-uk","product-tag-shockwave-m5","product-tag-shockwave-s4-en-uk","specialty-fellows-residents-en-uk","specialty-interventional-cardiologists-en-uk","specialty-interventional-radiologists-en-uk","specialty-nurses-technologists-en-uk","specialty-vascular-surgeons-en-uk","technology-peripheral-ivl-en-uk"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/clinical-evidence\/6607","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/clinical-evidence"}],"about":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/types\/clinical-evidence"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media\/4004"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media?parent=6607"}],"wp:term":[{"taxonomy":"disease-state","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/disease-state?post=6607"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/format?post=6607"},{"taxonomy":"product-tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/product-tag?post=6607"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/specialty?post=6607"},{"taxonomy":"technology","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/technology?post=6607"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}