{"id":7226,"date":"2024-11-01T15:21:26","date_gmt":"2024-11-01T20:21:26","guid":{"rendered":"https:\/\/shockwavemedical.com\/ivl-coronary-artery-disease\/"},"modified":"2025-01-17T06:56:31","modified_gmt":"2025-01-17T12:56:31","slug":"cad-ivl","status":"publish","type":"page","link":"https:\/\/shockwavemedical.com\/en-eu\/disease-states\/cad-ivl\/","title":{"rendered":"IVL for Coronary Artery Disease"},"content":{"rendered":"\n<section id=\"block_6047d10b7b8dfe64caac60bc60bcd120\" class=\"block block--primary-header u-darkMode u-bgColor_primary\"\n\tstyle=\"--desktop-bg-image: url('https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Background-Pulses.png');\n\t\t\t\t --mobile-bg-image: url('');\">\n\n\t<div class=\"primary-header-container text_colors\">\n\n\t\t<!-- Heading -->\n\t\t<div class=\"heading\">\n\t\t\t<h1 class=\"main-heading\">Shockwave IVL for Coronary Artery Disease<\/h1>\n\t\t\t<h3 class=\"sub-heading\">A proven crack record: Shockwave coronary Intravascular Lithotripsy (IVL) is a paradigm-shifting device allowing interventional cardiologists to bridge the gap between predictably safe and consistently effective coronary calcium modification in patients suffering from calcified coronary artery disease. <\/h3>\n\t\t<\/div>\n\n\t\t<!-- Optional links -->\n\t\t\t\t\t<div class=\"links\">\n\t\t\t\t\n<a data-atom=\"button\" class=\"btn--line optional-button on-dark\" href=\"https:\/\/shockwavemedical.com\/en-eu\/ivl-overview\/\" target=\"_self\" aria-label=\"Shockwave IVL Overview and MOA - link to page\" >Shockwave IVL Overview and MOA<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\n<a data-atom=\"button\" class=\"btn--line optional-button on-dark\" href=\"https:\/\/shockwavemedical.com\/en-eu\/products\/shockwave-c2-plus\/\" target=\"_self\" aria-label=\"Shockwave C2+ - link to page\" >Shockwave C2+<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t<\/div>\n\t\t\n\t\t<!-- links - J&J -->\n\t\t\n\t\t<!-- Social share -->\n\t\t\t\t<!-- Foreground for Desktop -->\n\t\t\t\t\t<div class=\"desktop-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave_C2_Hero_Product_Updated.png\" alt=\"Shockwave C2+ device showing the generator and the \" role=\"img\" aria-label=\"Foreground image for desktop\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\n\t\t<!-- Foreground for Mobile -->\n\t\t\t\t\t<div class=\"mobile-foreground-file\">\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Shockwave_C2_Hero_Product_Updated.png\" alt=\"Shockwave C2+ device showing the generator and the \" role=\"img\" aria-label=\"Foreground image for mobile\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 955px; --smush-placeholder-aspect-ratio: 955\/970;\">\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_db71862ee49f4c480f07b7e7624ce9b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_292565f502d7a5df51cae1bc98a93023\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>The Importance of Treating Coronary Artery Disease (CAD)<\/h2>\n<p><span data-contrast=\"auto\">Coronary artery disease is a global problem that affects approximately 315 million people every year.<\/span><sup><span data-contrast=\"auto\">1<\/span><\/sup><span data-contrast=\"auto\"> In some CAD, calcified plaque limits blood flow in the larger arteries of the heart, which increases the risk of adverse side effects.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"3\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Over 30% of coronary lesions have severe to moderate coronary calcification<\/span><sup><span data-contrast=\"auto\">2<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/sup><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"3\" data-list-defn-props=\"{\"335552541\":1,\"335559685\":720,\"335559991\":360,\"469769226\":\"Symbol\",\"469769242\":[8226],\"469777803\":\"left\",\"469777804\":\"\uf0b7\",\"469777815\":\"hybridMultilevel\"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Coronary artery calcification increases procedural complications,<\/span><sup><span data-contrast=\"auto\">3, 4, 5, 6, 7<\/span><\/sup><span data-contrast=\"auto\"> impedes stent delivery<\/span><sup><span data-contrast=\"auto\">8<\/span><\/sup><span data-contrast=\"auto\"> and prevents stent expansion<\/span><sup><span data-contrast=\"auto\">2, 9<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/sup><\/li>\n<\/ul>\n<p><span data-contrast=\"auto\">Shockwave coronary IVL disrupts coronary calcium through its unique mechanism of action (MOA), modifying calcium in a safe, effective and intuitive manner prior to stent deployment.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_db71862ee49f4c480f07b7e7624ce9b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n<section id=\"block_fedbb423e11df11de0fe89bf3271f8fc\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors has-stat-callout on-dark\">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">Not the Same Old Drill: A Low-Risk, Sound Calcium Strategy<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<p class=\"featured-clinical-evidence--description\">Shockwave Medical is the first-ever manufacturer of coronary IVL products \u2014 the most studied and frequently used calcium modification strategy<sup>10<\/sup> in our field. Our commitment to clinical research, continuous innovation and meaningful physician collaboration has set a new standard of care that is shaping the future of treating calcified coronary artery disease.\u00a0<\/p>\n\t\t\t\n\t\t\t\n\t\t\t\n<section id=\"block_fedbb423e11df11de0fe89bf3271f8fc\" class=\"block block--stat-callout \" role=\"region\" aria-labelledby=\"statCalloutTitle\" aria-describedby=\"statCalloutDesc\">\n\t<h2 id=\"statCalloutTitle\" class=\"sr-only\">Statistics Callout<\/h2> <!-- Add a hidden heading for accessibility -->\n\t<p id=\"statCalloutDesc\" class=\"sr-only\">This section presents key statistical information with numbers and descriptions.<\/p> <!-- Hidden description -->\n\n\t<!-- Changing container to ul for better semantics -->\n\t<ul class=\"container\" role=\"list\">\n\t\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-0\" role=\"listitem\" aria-labelledby=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-0-number\" aria-describedby=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-0-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-0-number\">305<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-0-description\">\n\t\t\t\t\t\tPeer-reviewed journal publications\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-1\" role=\"listitem\" aria-labelledby=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-1-number\" aria-describedby=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-1-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-1-number\">7,949<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-1-description\">\n\t\t\t\t\t\tPublished patient outcomes\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t\t<!-- Each card is now an li element for semantic correctness -->\n\t\t\t<li class=\"card\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-2\" role=\"listitem\" aria-labelledby=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-2-number\" aria-describedby=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-2-description\">\n\t\t\t\t<div class=\"card-top\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-number\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-2-number\">600,000+<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-symbol\">\n\t\t\t\t\t\t\t<span><\/span>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t\t\t<div class=\"card-description font--p\" id=\"block_fedbb423e11df11de0fe89bf3271f8fc-card-2-description\">\n\t\t\t\t\t\tPatients treated\t\t\t\t\t<\/div>\n\t\t\t\t\n\t\t\t<\/li>\n\t\t\t\t<\/ul>\n<\/section>\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t<\/ul>\n<\/section>\n\n\n<section\n\tid=\"block_db71862ee49f4c480f07b7e7624ce9b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_5a750658a95159ba0819d2eb0d14cb7f\" class=\"block block--cta-button-bar text_colors \">\n\t<div class=\"cta-button-bar--container\">\n\t\t<h2 id=\"block_5a750658a95159ba0819d2eb0d14cb7f-heading\" class=\"heading\">\n\t\t\tShockwave C2+: Our Sound Solution for Coronary Artery Disease\t\t<\/h2>\n\t\t<div class=\"buttons\">\n\t\t\t\t\t\t\t<ul class=\"cta-button-bar--links-container\" role=\"list\" aria-label=\"Call-to-action buttons\">\n\t\t\t\t\t\t\t\t\t\t\t<li class=\"resource-list--link\" role=\"listitem\">\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"on-blue btn--primary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/products\/shockwave-c2-plus\/\" target=\"_self\" aria-label=\"Meet Shockwave C2+ - link to page\" >Meet Shockwave C2+<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_db71862ee49f4c480f07b7e7624ce9b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_ae132ae348b33978c0c3deff0dabc621\" class=\"block block--youtube-video-with-text-overlay text_colors \">\n\t<div class=\"block__container\">\n\t\t<div class=\"thumbnail\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/shockwave-c2.jpg\" alt=\"Shockwave C2+ IVL Animation (Global)\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/>\n\t\t\t\t\t\t<div class=\"play-button-container\">\n\t\t\t\t<button type=\"button\" aria-label=\"Play video\" class=\"play-button btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-solid fa-play\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t<!-- Heading, description, and button -->\n\t\t<div class=\"heading-description-button\">\n\t\t\t\t\t\t\t<h2 class=\"heading\">\n\t\t\t\t\tSee How Shockwave C2+ Works \t\t\t\t<\/h2>\n\t\t\t\n\t\t\t\t\t\t\t<p class=\"description\">\n\t\t\t\t\tThe Shockwave IVL system creates pulsatile sonic pressure waves to modify coronary calcium in a low-risk manner that\u2019s effective and intuitive.\t\t\t\t<\/p>\n\t\t\t\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div class=\"video-modal\" role=\"dialog\" aria-modal=\"true\" aria-labelledby=\"modal-title-block_ae132ae348b33978c0c3deff0dabc621\" style=\"display: none;\">\n\t\t\t\t<button type=\"button\" aria-label=\"Close modal\" class=\"modal-close btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-xmark\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t\t<div class=\"modal-content\">\n\t\t\t\t\t<h2 id=\"modal-title-block_ae132ae348b33978c0c3deff0dabc621\" class=\"sr-only\">Video Player<\/h2>\n\t\t\t\t\t<lite-youtube videoid=\"G5CcNz1r5d8\" style=\"width: 100%; height: 100%;\" title=\"Shockwave C2+ IVL Animation (Global)\"><\/lite-youtube>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_6999110a22d687dd7cde9836ca16bd81\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 0px; --aboveMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_d0a2f64cca8c025dd46c058ebbfe584d\" class=\"block block--content-3-or-4-up text_colors \" aria-labelledby=\"section-heading-block_d0a2f64cca8c025dd46c058ebbfe584d\">\n\t<div class=\"container\">\n\n\t\t<!-- Header -->\n\t\t\t\t\t<header class=\"heading-row\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"section-heading-block_d0a2f64cca8c025dd46c058ebbfe584d\" class=\"optional-heading\">\n\t\t\t\t\t\tSee How Shockwave IVL Performs Across Calcium Morphologies\t\t\t\t\t<\/h2>\n\t\t\t\t\n\t\t\t\t\t\t\t<\/header>\n\t\t\n\t\t<!-- Cards Section -->\n\t\t<ul class=\"cards three-cards\" role=\"list\">\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Concentric-calcium-morphology-image.png\"\n\t\t\t\t\t\t\t\talt=\"Cross-sectional illustration of an artery with concentric calcified plaque buildup\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 555px; --smush-placeholder-aspect-ratio: 555\/310;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Shockwave IVL & Concentric Calcium<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/disease-states\/cad-ivl\/concentric\/\" target=\"_self\" aria-label=\"Read more about Shockwave IVL & Concentric Calcium\" >Explore More<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Eccentric-calcium-morphology-image.png\"\n\t\t\t\t\t\t\t\talt=\"Cross-sectional illustration of an artery with eccentric calcified plaque buildup\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 555px; --smush-placeholder-aspect-ratio: 555\/310;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Shockwave IVL & Eccentric Calcium\u202f<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/disease-states\/cad-ivl\/eccentric\/\" target=\"_self\" aria-label=\"Read more about Shockwave IVL & Eccentric Calcium\u202f\" >Explore More<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t\t<li class=\"card content-3-or-4-up-card three-cards\" role=\"listitem\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"card-image\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/Nodular-calcium-morphology-image.png\"\n\t\t\t\t\t\t\t\talt=\"Cross-sectional illustration of an artery with nodular calcified plaque buildup\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 555px; --smush-placeholder-aspect-ratio: 555\/310;\" \/>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t\t<!-- Card Content -->\n\t\t\t\t\t<div class=\"card-heading-description-link\">\n\t\t\t\t\t\t<h3 class=\"card-heading\">Shockwave IVL & Nodular Calcium<\/h3>\n\n\t\t\t\t\t\t<div class=\"card-description-link\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n<a data-atom=\"button\" class=\"card-link btn--tertiary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/disease-states\/cad-ivl\/nodular\/\" target=\"_self\" aria-label=\"Read more about Shockwave IVL & Nodular Calcium\" >Explore More<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t<\/ul>\n\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_db71862ee49f4c480f07b7e7624ce9b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_5f2bcb4958cd4cc38c51901b5474525f\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<h2>Backed By Clinical Evidence<\/h2>\n<p>Multiple clinical trials demonstrate coronary IVL\u2019s safety, efficacy and intuitiveness within global patient populations.<\/p>\n<table style=\"border-collapse: collapse; width: 100%;\">\n<tbody>\n<tr>\n<td style=\"width: 14.2857%;\"><\/td>\n<td style=\"width: 14.2857%;\">DISRUPT CAD I<\/td>\n<td style=\"width: 14.2857%;\">DISRUPT CAD II<\/td>\n<td style=\"width: 14.2857%;\">DISRUPT CAD III<\/td>\n<td style=\"width: 14.2857%;\">DISRUPT CAD IV<\/td>\n<td style=\"width: 14.2857%;\">DISRUPT CAD Pooled<\/td>\n<td style=\"width: 14.2857%;\">DISRUPT CAD Pooled OCT<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 14.2857%;\"><strong>Study design<\/strong><\/td>\n<td style=\"width: 14.2857%;\">Single arm, safety & feasibility<\/td>\n<td style=\"width: 14.2857%;\">Single arm, post-market, safety & effectiveness<\/td>\n<td style=\"width: 14.2857%;\">Single arm, IDE, safety & effectiveness<\/td>\n<td style=\"width: 14.2857%;\">Single arm, pre-market, safety & effectiveness<\/td>\n<td style=\"width: 14.2857%;\">Individual patient data (IPD) pooled analysis of the DISRUPT CAD I-IV studies<\/td>\n<td style=\"width: 14.2857%;\">Individual patient data (IPD) pooled analysis of the DISRUPT CAD I-IV OCT sub-studies<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 14.2857%;\"><strong>Number of patients<\/strong><\/td>\n<td style=\"width: 14.2857%;\">60<\/td>\n<td style=\"width: 14.2857%;\">120<\/td>\n<td style=\"width: 14.2857%;\">384<\/td>\n<td style=\"width: 14.2857%;\">64<\/td>\n<td style=\"width: 14.2857%;\"><strong>628<\/strong><\/td>\n<td style=\"width: 14.2857%;\">\u2013<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 14.2857%;\"><strong>Number of patients in OCT sub-study<\/strong><\/td>\n<td style=\"width: 14.2857%;\">31<\/td>\n<td style=\"width: 14.2857%;\">47<\/td>\n<td style=\"width: 14.2857%;\">100<\/td>\n<td style=\"width: 14.2857%;\">71<\/td>\n<td style=\"width: 14.2857%;\">\u2013<\/td>\n<td style=\"width: 14.2857%;\"><strong>262<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 14.2857%;\"><strong>Number of sites<\/strong><\/td>\n<td style=\"width: 14.2857%;\">7<\/td>\n<td style=\"width: 14.2857%;\">15<\/td>\n<td style=\"width: 14.2857%;\">47<\/td>\n<td style=\"width: 14.2857%;\">8<\/td>\n<td style=\"width: 14.2857%;\">72<\/td>\n<td style=\"width: 14.2857%;\">72<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 14.2857%;\"><strong>Regions<\/strong><\/td>\n<td style=\"width: 14.2857%;\">AU, EU<\/td>\n<td style=\"width: 14.2857%;\">EU<\/td>\n<td style=\"width: 14.2857%;\">U.S., EU<\/td>\n<td style=\"width: 14.2857%;\">Japan<\/td>\n<td style=\"width: 14.2857%;\">AU, EU, U.S., Japan<\/td>\n<td style=\"width: 14.2857%;\">AU, EU, U.S., Japan<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t<\/div>\n\t<\/section>\n\n<section id=\"block_7c9cc452400ae52035a8e20327bd3bd6\" class=\"block block--featured-clinical-evidence \" aria-labelledby=\"featured-clinical-evidence-title\">\n\t\t\t<div class=\"featured-clinical-evidence--top text_colors \">\n\t\t\t<div class=\"featured-clinical-evidence--title\">\n\t\t\t\t\t\t\t\t\t<h2 id=\"featured-clinical-evidence-title\" class=\"heading\">Featured Clinical Evidence Studies<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-top u--hidden u-md-block\">\n\t\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/\" target=\"_self\" aria-label=\"Explore All Clinical Evidence - link to page\" >Explore All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence__btn-wrap featured-clinical-evidence__btn-wrap-bottom u--block u-md-hidden\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\" btn--secondary\" href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/\" target=\"_self\" aria-label=\"Explore All Clinical Evidence - link to page\" >Explore All Clinical Evidence<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-light\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\n\t\t\t\t\t<\/div>\n\t\t<ul class=\"featured-clinical-evidence-list text_colors\" role=\"list\">\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-8003\" aria-describedby=\"post-category-8003 post-excerpt-8003\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-8003\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/cad-iii\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT CAD III\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-8003\">\n\t\t\t\t\t\tLargest and most rigorous Shockwave study showcasing the safety, effectiveness and ease of use of Shockwave coronary IVL\u202f.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-8003\">\n\t\t\t\t\t\tCoronary IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-8041\" aria-describedby=\"post-category-8041 post-excerpt-8041\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-8041\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/cad-pooled\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT CAD Pooled\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-8041\">\n\t\t\t\t\t\tThe\u202flargest systematic assessment of Shockwave coronary Intravascular Lithotripsy (IVL) to date based on individual patient data from DISRUPT CAD I\u2013IV.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-8041\">\n\t\t\t\t\t\tCoronary IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t\t\t\t<li class=\"featured-clinical-evidence-item\" role=\"listitem\" aria-labelledby=\"post-title-8045\" aria-describedby=\"post-category-8045 post-excerpt-8045\">\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--text-container\" id=\"post-title-8045\">\n\t\t\t\t\t\t<a href=\"https:\/\/shockwavemedical.com\/en-eu\/clinical-evidence\/cad-pooled-oct-subgroup\/\" class=\"featured-clinical-evidence-item--title\">\n\t\t\t\t\t\t\tDISRUPT CAD Pooled OCT Subgroup Analysis\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#5B6770\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t\t<div class=\"featured-clinical-evidence-item--arrow-hover\" aria-hidden=\"true\"><svg width=\"25\" height=\"27\" viewBox=\"0 0 25 27\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M3.5 26H21a2.5 2.5 0 002.5-2.5V7.875L16.625 1H6a2.5 2.5 0 00-2.5 2.5v3.75\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><path d=\"M16 1v7.5h7.5M4.75 19.75a3.75 3.75 0 100-7.498 3.75 3.75 0 000 7.498v0zm5 1.25l-1.875-1.875\" stroke=\"#00D2FF\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--excerpt\" id=\"post-excerpt-8045\">\n\t\t\t\t\t\tIndividual patient data pooled from DISRUPT CAD I-IV to see Shockwave IVL outcomes, fracture analysis and stent expansion predictors.\t\t\t\t\t<\/div>\n\t\t\t\t\t<div class=\"featured-clinical-evidence-item--category\" id=\"post-category-8045\">\n\t\t\t\t\t\tCoronary IVL\t\t\t\t\t<\/div>\n\t\t\t\t<\/li>\n\t\t\t<\/ul>\n<\/section>\n\n\n<section\n\tid=\"block_db71862ee49f4c480f07b7e7624ce9b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_4c161fa2807128242a4655c8331c916c\" class=\"block block--youtube-video-with-text-overlay text_colors \">\n\t<div class=\"block__container\">\n\t\t<div class=\"thumbnail\">\n\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/game-on.png\" alt=\"Youtube video\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" style=\"--smush-placeholder-width: 1905px; --smush-placeholder-aspect-ratio: 1905\/1006;\" \/>\n\t\t\t\t\t\t<div class=\"play-button-container\">\n\t\t\t\t<button type=\"button\" aria-label=\"Play video\" class=\"play-button btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-solid fa-play\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\t<!-- Heading, description, and button -->\n\t\t<div class=\"heading-description-button\">\n\t\t\t\t\t\t\t<h2 class=\"heading\">\n\t\t\t\t\tGame On: Calcium Crush \t\t\t\t<\/h2>\n\t\t\t\n\t\t\t\t\t\t\t<p class=\"description\">\n\t\t\t\t\tPut your skills to the test and tackle complex calcified lesions in a novel digital environment. Calcium Crush combines fun and skill-building, allowing you to practice your Shockwave C2+\u202fpulse management strategy and hone your Shockwave IVL skills.*\t\t\t\t<\/p>\n\t\t\t\n\t\t\t\t\t\t\t<div class=\"optional-button-container\">\n\t\t\t\t\t\n<a data-atom=\"button\" class=\"optional-button on-blue btn--primary\" href=\"https:\/\/showcase.lvlex.link\/shkweb?channel=website\" target=\"_self\" aria-label=\"Play Calcium Crush Now - link to page\" rel=\"noopener\">Play Calcium Crush Now<i aria-hidden=\"true\" class=\"fa-sharp fa-arrow-right fa-solid\"><\/i><\/a>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div class=\"video-modal\" role=\"dialog\" aria-modal=\"true\" aria-labelledby=\"modal-title-block_4c161fa2807128242a4655c8331c916c\" style=\"display: none;\">\n\t\t\t\t<button type=\"button\" aria-label=\"Close modal\" class=\"modal-close btn\">\n\t\t\t\t\t<i class=\"fa-sharp fa-regular fa-xmark\" aria-hidden=\"true\"><\/i>\n\t\t\t\t<\/button>\n\t\t\t\t<div class=\"modal-content\">\n\t\t\t\t\t<h2 id=\"modal-title-block_4c161fa2807128242a4655c8331c916c\" class=\"sr-only\">Video Player<\/h2>\n\t\t\t\t\t<lite-youtube videoid=\"RXCiN9rIX4Y\" style=\"width: 100%; height: 100%;\" title=\"Youtube video\"><\/lite-youtube>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/section>\n\n<section\n\tid=\"block_6999110a22d687dd7cde9836ca16bd81\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 0px; --aboveMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>\n\n\n<section id=\"block_4c1e4611a8d80618d2c68cd3ca37577b\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<hr \/>\n<p><span class=\"legal_copy\">*Calcium Crush is not available in all countries, please contact your local sales representative for details.<\/span><\/p>\n<p><span class=\"legal_copy\">1: Stark, B., Johnson, C., & Gregory Andrew Roth. (2024). Global Prevalence of Coronary Artery Disease: An Update from The Global Burden of Disease Study. Journal of the American College of Cardiology, 83(13), 2320-2320.<br \/>\n2: Ge\u0301ne\u0301reux P, et al. JACC 2014; 63(18);1845-54.<br \/>\n3: Madhavan MV, Tarigopula M, Mintz GS, Maehara A, Stone GW, G\u00e9n\u00e9reux P. Coronary artery calcification: pathogenesis and prognostic implications. J Am Coll Cardiol 2014;63:1703.<br \/>\n4: Chambers JW, Feldman RL, Himmelstein SI, et al. Pivotal trial to evaluate the safety and efficacy of the Orbital Atherectomy System In Treating De Novo, Severely Calcified Coronary Lesions (ORBIT II). J Am Coll Cardiol Intv 2014;7:510-8.<br \/>\n5: Genereux P, Lee AC, Kim CY, et al. Orbital atherectomy for treating de novo severely calcified coronary narrowing (1-year results from the pivotal ORBIT II Trial). Am J Cardiol 2015;115: 1685-90.<br \/>\n6: Yamamoto MH, Maehara A, Karimi Galougahi K, et al. Mechanisms of orbital versus rotational atherectomy plaque modification in severely calcified lesions assessed by optical coh\u00e9rence tomography. J Am Coll Cardiol Intv 2017;10: 2584-6.<br \/>\n7: Kini AS, Vengrenyuk Y, Pena J, et al. Optical coherence tomography assessment of the mechanistic effects of rotational and orbital atherectomy in severely calcified coronary lesions. Catheter Cardiovasc Interv 2015;86:1024-32.<br \/>\n8: Ferrer Gracia MC, et al. Failure in the implantation of drug eluting stents. Frequency and related factors. Med Intensiva. 2007.<br \/>\n9: Mintz, G; I. J Am Coll Cardiol Imaging 2015;8(4): 461-71.<br \/>\n10: Neel Butala et al. \u201cUse of Calcium Modification During Percutaneous Coronary Intervention After Introduction of Coronary Intravascular Lithotripsy\u201d Journal of the Society for Cardiovascular Angiography & Interventions. 2024; DOI: 10.1016\/j.jscai.2023.101254.<br \/>\n11: Robert Riley et al. \u201cSCAI expert consensus statement on the management of calcified coronary lesions.\u201d J Soc Cardiovasc Angiogr Interv. 2024.<br \/>\n12: Ziad Ali et al. \u201cSafety and Effectiveness of Coronary Intravascular Lithotripsy for Treatment of Calcified Nodules.\u201d JACC Cardiovasc Interv. 2023.<br \/>\n13; Ziad Ali et al. \u201cImpact of Calcium Eccentricity on the Safety and Effectiveness of Coronary Intravascular Lithotripsy: Pooled Analysis From the Disrupt CAD Studies.\u201d Cardiovascular Interv. 2023.\u00a0<\/span><\/p>\n\t<\/div>\n\t<\/section>\n\n<section\n\tid=\"block_db71862ee49f4c480f07b7e7624ce9b1\"\n\tclass=\"block block--spacer-with-optional-divider \"\n\taria-label=\"Spacer section with optional divider\">\n\t<div class=\"spacer-with-optional-divider-container container\">\n\n\t\t<!-- Space Above -->\n\t\t<div\n\t\t\tclass=\"space-above\"\n\t\t\tstyle=\"--aboveDesktop: 60px; --aboveMobile: 30px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t\t<!-- Optional Divider -->\n\t\t\n\t\t<!-- Space Below -->\n\t\t<div\n\t\t\tclass=\"space-below\"\n\t\t\tstyle=\"--belowDesktop: 0px; --belowMobile: 0px;\"\n\t\t\taria-hidden=\"true\"\n\t\t\trole=\"presentation\">\n\t\t<\/div>\n\n\t<\/div>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>Shockwave coronary IVL enables safe, effective coronary calcium modification for patients with calcified coronary artery disease.<\/p>\n","protected":false},"author":13,"featured_media":3947,"parent":9780,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"content-type":"","footnotes":""},"class_list":["post-7226","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/pages\/7226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/comments?post=7226"}],"version-history":[{"count":0,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/pages\/7226\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/pages\/9780"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media\/3947"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media?parent=7226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}