{"id":8902,"date":"2022-03-22T17:34:00","date_gmt":"2022-03-22T22:34:00","guid":{"rendered":"https:\/\/shockwavemedical.com\/education\/men-vs-women-in-pci-outcomes-whats-the-consensus\/"},"modified":"2025-01-07T09:54:52","modified_gmt":"2025-01-07T15:54:52","slug":"men-vs-women-in-pci-outcomes-whats-the-consensus","status":"publish","type":"post","link":"https:\/\/shockwavemedical.com\/en-eu\/education\/men-vs-women-in-pci-outcomes-whats-the-consensus\/","title":{"rendered":"Men vs Women in PCI Outcomes: What\u2019s the Consensus?"},"content":{"rendered":"\n<section id=\"block_a3be6d020ff01f8ac3f686ba881d6995\" class=\"block block--wysiwyg wysiwyg_styles u-bgColorNone container\">\n\t<div class=\"u-wysiwyg u-animation\">\n\t\t<p>Some of us know the data. Some don\u2019t. The question once you do is where we go from here to bridge the gender inequality gap?<\/p>\n<p>To help address this question, SCAI just published in the Journal of the Society for Cardiovascular Angiography & Interventions (JSCAI), the new official journal of SCAI, an \u201cExpert Consensus on Sex Specific Considerations in Myocardial Revascularization.\u201d Shockwave coronary IVL was referenced in the consensus as a potential first-line therapy for plaque modification of calcified lesions in women specifically.<\/p>\n<p>\u00a0<\/p>\n<p><strong>JSCAI Publication:\u00a0Expert Consensus on Sex-Specific Considerations in Myocardial Revascularization<\/strong><\/p>\n<p>Read the Publication Here:\u00a0\u00a0<a href=\"https:\/\/www.jscai.org\/article\/S2772-9303(21)00016-8\/fulltext\" target=\"_blank\" rel=\"noopener\">https:\/\/www.jscai.org\/article\/S2772-9303(21)00016-8\/fulltext<\/a><\/p>\n<p>The Expert Consensus brings to light the gender disparities in cardiovascular disease, identifies gaps in evidence regarding cardiovascular outcomes in women, inform clinicians on best practices most relevant to female patients and guides future research priorities.<\/p>\n<p>And for more engaging content on this topic, here is a great discussion hosted by\u00a0SCAI Conversations in Interventional Cardiology with Drs. Alexandra Lansky, J. Dawn Abbott, Jennifer Tremmel, Roxana Mehran, and Suzanne Baron.<\/p>\n<div class=\"video\"><iframe title=\"YouTube video player\" data-src=\"https:\/\/www.youtube.com\/embed\/xTgagSRtOo0?si=i8HjKTR2Ybew3Fu-\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" class=\"lazyload\" data-load-mode=\"1\"><\/iframe><\/div>\n<div><\/div>\n<div><\/div>\n<div>\n<p><strong>SCAI Conversations in Interventional Cardiology Video CME<\/strong><\/p>\n<p><a href=\"https:\/\/protect-us.mimecast.com\/s\/b8XaC5yg9jIXKxYUO6X6E?domain=scaipro.scai.org\" target=\"_blank\" rel=\"noopener\">Sex-Specific Considerations in Myocardial Revascularization (scai.org)<\/a><\/p>\n<p>Shockwave coronary IVL was referenced in the consensus, stating: \u201cWhile additional evidence is needed, these results (i.e. DISRUPT CAD Pooled Gender Analysis) taken in the context of outcomes with atherectomy devices suggest that IVL may emerge as a first-line therapy for plaque modification of calcified lesions in women specifically.\u201d<\/p>\n<p>We have included the resources below to learn more about the DISRUPT CAD Pooled Gender Analysis and role that coronary IVL plays in calcium modification in men and women.<\/p>\n<p>\u00a0<\/p>\n<\/div>\n<p><strong>SCAI Conversations in Interventional Cardiology Video CME<\/strong><\/p>\n<p><a href=\"https:\/\/protect-us.mimecast.com\/s\/9WsbC82l6mU2NVjtnDl3D?domain=scaipro.scai.org\" target=\"_blank\" rel=\"noopener\">Sex-Specific Outcomes After Coronary IVL: Disrupt CAD Studies (scai.org)<\/a><\/p>\n<p>\u00a0<\/p>\n<p>Plus, the\u00a0<a href=\"https:\/\/www.jscai.org\/article\/S2772-9303(21)00011-9\/fulltext\" target=\"_blank\" rel=\"noopener\"><strong>JSCAI CAD Pooled Gender Analysis Publication<\/strong><\/a>\u00a0&\u00a0<a href=\"https:\/\/shockwavemedical.com\/wp-content\/uploads\/2024\/11\/CAD-Pooled-Gender-Presentation-TCT-2021-Lansky.pdf\"><strong>DISRUPT CAD Pooled Gender Analysis TCT Data Slides<\/strong><\/a>.<\/p>\n<hr \/>\n<div>\n<p><strong><span class=\"legal_copy\">Coronary Important Safety Information:<\/span><\/strong><\/p>\n<p><span class=\"legal_copy\"> In the United States: Rx only.<\/span><\/p>\n<p><span class=\"legal_copy\"> Indications for Use\u2014The Shockwave Intravascular Lithotripsy (IVL) System with the Shockwave C2\u00a0Coronary IVL Catheter is indicated for lithotripsy-enabled, low-pressure balloon dilatation of severely calcified, stenotic\u00a0de novo\u00a0coronary arteries prior to stenting. <\/span><\/p>\n<p><span class=\"legal_copy\">Contraindications\u2014The Shockwave C2\u00a0Coronary IVL System is contraindicated for the following: This device is not intended for stent delivery. This device is not intended for use in carotid or cerebrovascular arteries. <\/span><\/p>\n<p><span class=\"legal_copy\">Warnings\u2014 Use the IVL Generator in accordance with recommended settings as stated in the Operator\u2019s Manual. The risk of a dissection or perforation is increased in severely calcified lesions undergoing percutaneous treatment, including IVL. Appropriate provisional interventions should be readily available. Balloon loss of pressure was associated with a numerical increase in dissection which was not statistically significant and was not associated with MACE.\u00a0 Analysis indicates calcium length is a predictor of dissection and balloon loss of pressure.\u00a0 IVL generates mechanical pulses which may cause atrial or ventricular capture in bradycardic patients. In patients with implantable pacemakers and defibrillators, the asynchronous capture may interact with the sensing capabilities. Monitoring of the electrocardiographic rhythm and continuous arterial pressure during IVL treatment is required.\u00a0 In the event of clinically significant hemodynamic effects, temporarily cease delivery of IVL therapy. <\/span><\/p>\n<p><span class=\"legal_copy\">Precautions\u2014 Only to be used by physicians trained in angiography and intravascular coronary procedures. Use only the recommended balloon inflation medium. Hydrophilic coating to be wet only with normal saline or water and care must be taken with sharp objects to avoid damage to the hydrophilic coating.\u00a0Appropriate anticoagulant therapy should be administered by the physician.\u00a0Precaution should be taken when treating patients with previous stenting within 5mm of target lesion. <\/span><\/p>\n<p><span class=\"legal_copy\">Potential adverse effects consistent with standard based cardiac interventions include\u2013 Abrupt vessel closure \u2013 Allergic reaction to contrast medium, anticoagulant and\/or antithrombotic therapy-Aneurysm-Arrhythmia-Arteriovenous fistula-Bleeding complications-Cardiac tamponade or pericardial effusion-Cardiopulmonary arrest-Cerebrovascular accident (CVA)-Coronary artery\/vessel occlusion, perforation, rupture or dissection-Coronary artery spasm-Death-Emboli (air, tissue, thrombus or atherosclerotic emboli)-Emergency or non-emergency coronary artery bypass surgery-Emergency or non-emergency percutaneous coronary intervention-Entry site complications-Fracture of the guide wire or failure\/malfunction of any component of the device that may or may not lead to device embolism, dissection, serious injury or surgical intervention-Hematoma at the vascular access site(s)-Hemorrhage-Hypertension\/Hypotension-Infection\/sepsis\/fever-Myocardial Infarction-Myocardial Ischemia or unstable angina-Pain-Peripheral Ischemia-Pseudoaneurysm-Renal failure\/insufficiency-Restenosis of the treated coronary artery leading to revascularization-Shock\/pulmonary edema-Slow flow, no reflow, or abrupt closure of coronary artery-Stroke-Thrombus-Vessel closure, abrupt-Vessel injury requiring surgical repair-Vessel dissection, perforation, rupture, or spasm. Risks identified as related to the device and its use:\u00a0Allergic\/immunologic reaction to the catheter material(s) or coating-Device malfunction, failure, or balloon loss of pressure leading to device embolism, dissection, serious injury or surgical intervention-Atrial or ventricular extrasystole-Atrial or ventricular capture. <\/span><\/p>\n<p><span class=\"legal_copy\">Prior to use, please reference the Instructions for Use for more information on warnings, precautions and adverse events.\u00a0\u00a0<a href=\"https:\/\/shockwavemedical.com\/en-eu\/ifu\/\">https:\/\/shockwavemedical.com\/IFU <\/a><\/span><\/p>\n<p><span class=\"legal_copy\">Please contact your local Shockwave representative for specific country availability and refer to the Shockwave C2\u00a0instructions for use containing important safety information.<\/span><\/p>\n<\/div>\n\t<\/div>\n\t<\/section>","protected":false},"excerpt":{"rendered":"<p>The Expert Consensus brings to light the gender disparities in cardiovascular disease and informs clinicians on best practices most relevant to female patients<\/p>\n","protected":false},"author":2,"featured_media":8545,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":[203],"meta":{"_acf_changed":true,"content-type":"","footnotes":""},"categories":[17,1],"tags":[],"disease-state":[159],"education-topic":[183],"product-tag":[],"specialty":[295,328,332,344],"technology":[316],"class_list":["post-8902","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-en-uk","category-uncategorized","disease-state-coronary-artery-disease-en-uk","education-topic-best-practices-en-uk","format-article-en-uk","specialty-fellows-residents-en-uk","specialty-interventional-cardiologists-en-uk","specialty-interventional-radiologists-en-uk","specialty-vascular-surgeons-en-uk","technology-coronary-ivl-en-uk"],"acf":[],"_links":{"self":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/posts\/8902","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/comments?post=8902"}],"version-history":[{"count":0,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/posts\/8902\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media\/8545"}],"wp:attachment":[{"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/media?parent=8902"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/categories?post=8902"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/tags?post=8902"},{"taxonomy":"disease-state","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/disease-state?post=8902"},{"taxonomy":"education-topic","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/education-topic?post=8902"},{"taxonomy":"format","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/format?post=8902"},{"taxonomy":"product-tag","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/product-tag?post=8902"},{"taxonomy":"specialty","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/specialty?post=8902"},{"taxonomy":"technology","embeddable":true,"href":"https:\/\/shockwavemedical.com\/en-eu\/wp-json\/wp\/v2\/technology?post=8902"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}