Shockwave IVL for Peripheral Artery Disease

The sound calcium solution: Shockwave Intravascular Lithotripsy (IVL) is your peripheral powerhouse when it comes to treating calcified peripheral artery disease (PAD). Our low-risk, effective mechanism of action (MOA) delivers consistent results and powerful calcium-cracking capabilities — even in the hardest-to-reach vessels.

Shockwave IVL Overview and MOA Shockwave IVL for Coronary Artery Disease
Shockwave IVL generator with three peripheral catheters
Shockwave IVL generator with three peripheral catheters

The Importance of Treating Peripheral Artery Disease

Affecting more than eight million people aged 40 and older in the United States, the calcium buildup associated with PAD increases the risk of coronary artery disease (CAD) and cerebrovascular disease, which could lead to a heart attack or stroke.1, 2

What’s more, chronic limb-threatening ischemia (CLTI) is the most advanced and serious form of PAD, impacting nearly two million patients in the U.S. In fact, CLTI:3

  • Is associated with 40% major amputations at one year
  • Has a 50% mortality rate at 5 years, worse than most forms of cancer

Plaque in the arteries evolves into calcium deposits, which can narrow the artery and make it rigid and more difficult to reopen with conventional treatments, including balloons, which attempt to crack the calcium when inflated to high pressure, and atherectomy, which drills through the calcium to open the artery.4

Shockwave peripheral IVL can help treat these calcium deposits through its unique MOA, which produces sonic pressure waves that safely fracture calcium in the artery wall and restore blood flow both above and below the knee.

Shockwave Peripheral IVL: Sized for Iliacs, Fem-pop and Below the Knee

  • Predictably safe

    Safely modify calcium while significantly reducing the risk of complications to make procedures more predictable and efficient

  • Distinctly intuitive

    A unique MOA on an intuitive platform is simple to learn and effective from the first case

  • Consistently effective

    Powerfully disrupts superficial and deep calcium across multiple vessel beds, with low residual stenosis
Shockwave IVL Mechanism of Action (MOA) Overview

Shockwave IVL Mechanism of Action (MOA)

Get an up-close and detailed look at how Shockwave IVL works, quickly and powerfully.

Products

Shockwave peripheral IVL for specialized use cases: Dive deeper into peripheral IVL above and below the knee and how it can be used to enable access of transcatheter aortic valve replacement (TAVR) and endovascular aneurysm repair (EVAR).

  • Sound Evidence: The DISRUPT PAD Clinical Program

    We’ve supported research into the safety and effectiveness of Shockwave IVL in the periphery, and the proof is clear: You can count on it.

    See the studies

  • Shockwave Peripheral IVL Reimbursement

    Shockwave peripheral IVL has reimbursement in the outpatient, ambulatory surgical centers (ASC) and inpatient setting for Shockwave IVL use both above- and below-the-knee. 

    Explore reimbursement

1: https://www.nhlbi.nih.gov/health/peripheral-artery-disease
2: https://www.cdc.gov/heart-disease/about/peripheral-artery-disease.html
3: https://www.ahajournals.org/doi/full/10.1161/CIRCOUTCOMES.120.007539
4: Hill J., Kereiakes D., et al. IVL for Severely Calcified Coronary Artery Disease. J Am Coll Cardiol. 2020 Dec, 76 (22) 2635–2646. https://www.jacc.org/doi/full/10.1016/j.jacc.2020.09.603