Finally, Calcium Will Meet Its Match

Promising Treatments Have Come Up Short In Addressing the Growing Burden of Calcium

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Current Landscape of

Calcium Burden and Modification Tools

Global Population Ages = Incidence of Cardiovascular Calcium On the Rise
Calcium Increases Case Complexity & Decreases Treatment Effectiveness
Conventional Treatment Options Can Be Difficult to Learn, Perform and Master
Patients at an Increased Risk for Adverse Events Due to Calcium and Modification Tools

One of the reasons problematic calcium in cardiovascular disease has long been associated with worse clinical outcomes is that

existing solutions face common limitations.

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Unable to Dilate

High pressure balloons and modified balloons, such as scoring and cutting balloons, aren’t able to reliably dilate vessels containing rigid, severe calcium.
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Don't Address Deep Calcium

Current technologies – including high pressure and modified balloons, as well as atherectomy – only treat superficial calcium, leaving deep calcium unaddressed and potentially impacting procedural outcomes.1
1. Rocha-Singh et al, Peripheral arterial calcification: prevalence, mechanism, detection, and clinical implications, Catheter Cardiovasc Interv, 2014

Furthermore, conventional solutions have
inadequately addressed calcium by requiring physicians to make tradeoffs
when treating calcified lesions, including:

Increased
Risk
Increasing the risk of severe adverse events, including major dissections, perforation and distal emboli
Soft Tissue
Harm
Damaging the soft intimal tissue in order to modify the calcium
Additional
Cost
Incurring additional costs for secondary therapies when first-line therapies fail
Complicated
Tech
Performing complex cases with complicated technology and unpredictable outcomes

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